About this Research Topic
The last pandemic has caused massive damage all around the globe, resulting in researchers striving to design therapeutics to combat novel viruses like Coronavirus. This is not the first time an RNA virus has impacted human lives. According to History, every 100 years a pandemic occurs, and RNA viruses have been the prime cause of such devastation so far. For example, the outbreak of the Spanish Flu caused by Influenza A virus subtype H1N1 (negative-sense, single-stranded, segmented RNA virus) in 1918 cost many lives globally. Moreover, every year there are many cases of Ebola, Zika, Dengue viruses reported worldwide. The outbreak of these viruses put a question mark on the prevention and cure. Leading to the following question: are we ready for next pandemic? In this Research Topic, we will incorporate novel findings on therapeutic approaches on all aspects of RNA viruses, and on the efforts to be made to prevent a possible future pandemic, which is most likely to occur.
In this Research Topic, we plan to tackle the challenges caused by different RNA viruses which impact different parts of the globe. We will focus on the intriguing features of RNA viruses which will be helpful in designing potential drug targets. To achieve this, we will ascribe modern interdisciplinary techniques which might give us a wide perspective of how these potential drug targets can work.
Simultaneously, we plan to revisit the available drug targets against all RNA viruses, to consider whether they can be viable solutions to prevent viral activities.
We welcome submissions of the following article types: Original Research, Review, Mini Review, Perspective, General Commentary, Hypothesis and Theory, Methods, and Opinion. We welcome submissions that cover, but are not limited to, the following areas:
• Different level of biomolecular interactions crucial for RNA Virus infections, causing disease (for example Hepatitis C Virus causing Cancer, Rabies, Measles viruses from RNA virus family causing Neurogenerative Disorders)
• Small molecule-based studies using high throughput screening to design potential antivirals
• Repurposing current drugs to cover a wider range of RNA viruses and their new mechanism of action
In this Research Topic, we plan to tackle the challenges caused by different RNA viruses which impact different parts of the globe. We will focus on the intriguing features of RNA viruses which will be helpful in designing potential drug targets. To achieve this, we will ascribe modern interdisciplinary techniques which might give us a wide perspective of how these potential drug targets can work.
Simultaneously, we plan to revisit the available drug targets against all RNA viruses, to consider whether they can be viable solutions to prevent viral activities.
We welcome submissions of the following article types: Original Research, Review, Mini Review, Perspective, General Commentary, Hypothesis and Theory, Methods, and Opinion. We welcome submissions that cover, but are not limited to, the following areas:
• Different level of biomolecular interactions crucial for RNA Virus infections, causing disease (for example Hepatitis C Virus causing Cancer, Rabies, Measles viruses from RNA virus family causing Neurogenerative Disorders)
• Small molecule-based studies using high throughput screening to design potential antivirals
• Repurposing current drugs to cover a wider range of RNA viruses and their new mechanism of action
Keywords: RNA, virus, RNA virus, therapeutics, disease, infection, antivirals
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
