Adverse Effects of Cancer Chemotherapy: Anything New to Improve Tolerance and Reduce Sequelae?

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Editorial

22 March 2018

Editorial: Adverse Effects of Cancer Chemotherapy: Anything New to Improve Tolerance and Reduce Sequelae?

Kulmira Nurgali

,

R. Thomas Jagoe

and

Raquel Abalo

87,154 views

816 citations

Editors

3

Rey Juan Carlos University

Kulmira Nurgali

Institute of Health and Sport, College of Health and Biomedicine, Victoria University

McGill University

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The present Research Topic is based on the following facts:

- Cancer is one of the diseases with higher prevalence and morbi-mortality nowadays.
- Cancer chemotherapy is still greatly feared by the patients (and clinicians) because of the known adverse effects that may occur: nausea, emesis, alterations in blood-cell counting (anaemia, altered immune system and altered clotting), peripheral neuropathy, heart malfunctioning, kidney damage, cognitive loss…
- Current antineoplastic treatments have increased survival and we do not know much yet about the sequelae that they may leave in the survivors: cognitive dysfuntions, cardiovascular alterations, higher risk to gastrointestinal diseases, permanent sensory dysfuntions…
- Current prophylactic treatments to avoid/reduce/treat chemotherapy-induced adverse effects occurring during cycles are not always 100 per cent efficacious (or they may lose efficacy throughout cycles), may not be useful to avoid sequelae, or maybe even add their own side effects to patient discomfort…
- New approaches capable of improving tolerance and reduce sequelae of cancer chemotherapy are urgently needed.

We call authors from all over the world to submit original basic or clinical research or review articles describing the adverse effects of cancer chemotherapy and/or possible new strategies to avoid/reduce these effects, particularly those occurring in the long-term (sequelae), which are still highly unknown.

The present Research Topic is based on the following facts:

- Cancer is one of the diseases with higher prevalence and morbi-mortality nowadays.
- Cancer chemotherapy is still greatly feared by the patients (and clinicians) because of the known adverse effects that may occur: nausea, emesis, alterations in blood-cell counting (anaemia, altered immune system and altered clotting), peripheral neuropathy, heart malfunctioning, kidney damage, cognitive loss…
- Current antineoplastic treatments have increased survival and we do not know much yet about the sequelae that they may leave in the survivors: cognitive dysfuntions, cardiovascular alterations, higher risk to gastrointestinal diseases, permanent sensory dysfuntions…
- Current prophylactic treatments to avoid/reduce/treat chemotherapy-induced adverse effects occurring during cycles are not always 100 per cent efficacious (or they may lose efficacy throughout cycles), may not be useful to avoid sequelae, or maybe even add their own side effects to patient discomfort…
- New approaches capable of improving tolerance and reduce sequelae of cancer chemotherapy are urgently needed.

We call authors from all over the world to submit original basic or clinical research or review articles describing the adverse effects of cancer chemotherapy and/or possible new strategies to avoid/reduce these effects, particularly those occurring in the long-term (sequelae), which are still highly unknown.

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Editors

Rey Juan Carlos University

Kulmira Nurgali

Institute of Health and Sport, College of Health and Biomedicine, Victoria University

McGill University

Impact

228,007 Total views

167,662 Article views

51,875 Article downloads

8,470 Topic views

Published In

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Frontiers in Pharmacology

Pharmacology of Anti-Cancer Drugs

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Frontiers in Oncology

Pharmacology of Anti-Cancer Drugs

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