Patients with viral infection are at higher risk of secondary infections which include bacterial, viral, or parasitic and can lead to worse prognosis. In the setting of coinfection one viral infection may be preceded by a prior microbial infection or has a
concurrent or superinfection. In this setting, viral replication and infection status is modified through viral interference, interferons, defective interfering particles etc. In addition, coinfections can modulate virus virulence and cell death, thereby altering disease severity and epidemiology. However, contradictory results concerning the impact of coinfection on the outcomes of viral pathogenesis have also been observed and reported. Till date, data on the prevalence, pathogenesis, and outcomes of coinfection and superinfection are limited.
Thus, this Research Topic is focused on the impact of viral coinfection at the cellular level and on human health overall, as well as its clinical outcome. We invite researchers and clinicians to submit articles of any type (Original Research, Review, Methods, Perspective, Mini-Review, Opinion) on but not limited to the following topics:
-The presence and activities of two viral pathogens including virus production, enhancing or reducing disease severity at cellular level
-The clinical outcome of patients in viral coinfection
-Susceptibility of other infections in presence of a particular viral infection
Patients with viral infection are at higher risk of secondary infections which include bacterial, viral, or parasitic and can lead to worse prognosis. In the setting of coinfection one viral infection may be preceded by a prior microbial infection or has a
concurrent or superinfection. In this setting, viral replication and infection status is modified through viral interference, interferons, defective interfering particles etc. In addition, coinfections can modulate virus virulence and cell death, thereby altering disease severity and epidemiology. However, contradictory results concerning the impact of coinfection on the outcomes of viral pathogenesis have also been observed and reported. Till date, data on the prevalence, pathogenesis, and outcomes of coinfection and superinfection are limited.
Thus, this Research Topic is focused on the impact of viral coinfection at the cellular level and on human health overall, as well as its clinical outcome. We invite researchers and clinicians to submit articles of any type (Original Research, Review, Methods, Perspective, Mini-Review, Opinion) on but not limited to the following topics:
-The presence and activities of two viral pathogens including virus production, enhancing or reducing disease severity at cellular level
-The clinical outcome of patients in viral coinfection
-Susceptibility of other infections in presence of a particular viral infection
