About this Research Topic
Antimicrobial resistance (AMR), when pathogens resist drugs designed to inhibit them, is among the most leading global public health threats of the 21st century. Thus, AMR threatens human, animal, and environmental health globally. Moreover, the widespread misuse and uncontrolled prescription of antibiotics aggravates the AMR, diminishing antibiotics efficacy, including last-resort ones.
Most community members in rural settings are small-scale farmers, often living with their livestock inside the yards. Animal excreta may harbour pathogens, capable of infecting humans, posing a substantial human health risk. Inadequate disposal of animal excreta from household surroundings could result in the transmission of zoonotic pathogens by direct contact with contaminated fomites, soil, or water. Furthermore, using animal faeces as manure to enhance crop production leads to the transfer of antimicrobial-resistant pathogens and their associated genes to the environment. These pollutants may reach water bodies through runoff, posing a health risk, upon exposure, to resource-limited communities members using such water for personal and household hygiene, and irrigation.
This Research Topic aims to
- Report on the prevalence of AMR around the world from the environment, Animals and Humans
- Report on the potential risks associated with AMR acquired from zoonosis.
- Report on the causes of AMR around the world
- Report on the genes responsible for AMR
- Report on using the One Health approach to combat AMR
- Provide recent advances on the use of genomics in the fight against AMR
- Report on drivers of AMR in the various One Health compartments
- Identify alternatives to antibiotics, especially in animal farming, for combatting AMR
This topic’s scope includes
- The causes of Antimicrobial resistance
- The Antimicrobial resistance in the One Health concept
- The relationship between antimicrobial resistance and microbial pathogenesis
- The distribution of resistant infection
- Techniques used in AMR surveillance – culture, genomics
- Alternatives to antimicrobial use in animal farming
Most community members in rural settings are small-scale farmers, often living with their livestock inside the yards. Animal excreta may harbour pathogens, capable of infecting humans, posing a substantial human health risk. Inadequate disposal of animal excreta from household surroundings could result in the transmission of zoonotic pathogens by direct contact with contaminated fomites, soil, or water. Furthermore, using animal faeces as manure to enhance crop production leads to the transfer of antimicrobial-resistant pathogens and their associated genes to the environment. These pollutants may reach water bodies through runoff, posing a health risk, upon exposure, to resource-limited communities members using such water for personal and household hygiene, and irrigation.
This Research Topic aims to
- Report on the prevalence of AMR around the world from the environment, Animals and Humans
- Report on the potential risks associated with AMR acquired from zoonosis.
- Report on the causes of AMR around the world
- Report on the genes responsible for AMR
- Report on using the One Health approach to combat AMR
- Provide recent advances on the use of genomics in the fight against AMR
- Report on drivers of AMR in the various One Health compartments
- Identify alternatives to antibiotics, especially in animal farming, for combatting AMR
This topic’s scope includes
- The causes of Antimicrobial resistance
- The Antimicrobial resistance in the One Health concept
- The relationship between antimicrobial resistance and microbial pathogenesis
- The distribution of resistant infection
- Techniques used in AMR surveillance – culture, genomics
- Alternatives to antimicrobial use in animal farming
Keywords: Antibiotics, Antimicrobial resistance, Genomics, One Health, Pathogens, Zoonotic infections
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
