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About this Research Topic

Abstract Submission Deadline 04 December 2022
Manuscript Submission Deadline 05 January 2023

The Cellular Neurophysiology section in Frontiers in Cellular Neuroscience is delighted to present the ‘Reviews in’ series of article collections.

Reviews in Cellular Neurophysiology will publish high-quality scholarly review papers on key topics in Cellular Neurophysiology. This particular Research Topic will focus on “Neurophysiological mechanisms in the developing and adult rodent brain”.

Neurons wire together to form specific neuronal circuits whose distinct patterns of activity support a wide range of functions, from perception to cognition. Even an apparently simple task, such as the detection of a sensory stimulus, requires correlated patterns of activity between local and wider networks to elicit a functional outcome and direct distinct behaviours. Specific patterns of activity are generated also at rest, in absence of stimuli. The role of spontaneous activity in shaping neuronal circuit architecture is well established. Its role in information coding is at the center of an intense field of investigation, although several aspects remain to be elucidated. The patterns of neuronal activity are highly dynamic in face of the constantly changing flux of information and are modulated by the internal states of the individual, its previous experience (memory) as well as its expectation. In this scenario, a long-standing question is how the brain is capable to detect stimuli with respect to a noisy background and how it is capable to distinguish a stimulus coming from the external world with respect to an internally generate one. A growing body of evidence suggests that the neurophysiological mechanisms underlying sensory perception and integration rely on bottom-up and down-top processes. The hypothesis is that the brain uses an internal model (i.e. a generative model) to predict sensory inputs based on movements and past sensory experience. The neurophysiological mechanisms underlying perception are refined during development and are strongly affected in pathological conditions. This Research Topic aims to spotlight current advances in the neurophysiological mechanisms underlying sensory perception and integration, in physiological and pathological conditions, during development and in adulthood, with the ultimate goal to provide an updated vision on how the brain makes sense of the world to drive behaviour.


This Research Topic welcomes full-length, mini or systematic review papers. New articles will be added to this collection as they are published.

Keywords: Neurophysiological mechanisms, developing brain, adult brain, rodent, sensory perception, sensory integration


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

The Cellular Neurophysiology section in Frontiers in Cellular Neuroscience is delighted to present the ‘Reviews in’ series of article collections.

Reviews in Cellular Neurophysiology will publish high-quality scholarly review papers on key topics in Cellular Neurophysiology. This particular Research Topic will focus on “Neurophysiological mechanisms in the developing and adult rodent brain”.

Neurons wire together to form specific neuronal circuits whose distinct patterns of activity support a wide range of functions, from perception to cognition. Even an apparently simple task, such as the detection of a sensory stimulus, requires correlated patterns of activity between local and wider networks to elicit a functional outcome and direct distinct behaviours. Specific patterns of activity are generated also at rest, in absence of stimuli. The role of spontaneous activity in shaping neuronal circuit architecture is well established. Its role in information coding is at the center of an intense field of investigation, although several aspects remain to be elucidated. The patterns of neuronal activity are highly dynamic in face of the constantly changing flux of information and are modulated by the internal states of the individual, its previous experience (memory) as well as its expectation. In this scenario, a long-standing question is how the brain is capable to detect stimuli with respect to a noisy background and how it is capable to distinguish a stimulus coming from the external world with respect to an internally generate one. A growing body of evidence suggests that the neurophysiological mechanisms underlying sensory perception and integration rely on bottom-up and down-top processes. The hypothesis is that the brain uses an internal model (i.e. a generative model) to predict sensory inputs based on movements and past sensory experience. The neurophysiological mechanisms underlying perception are refined during development and are strongly affected in pathological conditions. This Research Topic aims to spotlight current advances in the neurophysiological mechanisms underlying sensory perception and integration, in physiological and pathological conditions, during development and in adulthood, with the ultimate goal to provide an updated vision on how the brain makes sense of the world to drive behaviour.


This Research Topic welcomes full-length, mini or systematic review papers. New articles will be added to this collection as they are published.

Keywords: Neurophysiological mechanisms, developing brain, adult brain, rodent, sensory perception, sensory integration


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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