Tissue engineering technology is a multidisciplinary technology to construct a composite system of seed cells, scaffolds, and bioactive factors. This technology has achieved good results in repairing or replacing biological tissues in a healthy state. However, in the pathological microenvironment, it often leads to damaged function of seed cells, inactivation of bioactive factors, and abnormal degradation or damage of scaffolds. Targeting the local microenvironment specifically to different diseases and designing specific tissue engineering strategies to repair and replace tissue damage is an urgent problem to be solved.
This Research Topic focuses on basic and applied research that adopts advanced materials in the establishment and repair of the pathological microenvironment to restore the functions of tissues and/or organs. The topic welcomes, but is not limited to, Original Research, Reviews, and Mini Reviews in the following research areas:
• Design, development, and evaluation of novel pathological models in vitro and in vivo
• Pathological microenvironment models for tissue and/or organ repair
• Advanced materials target specific pathological microenvironments
• The interaction between pathological microenvironments and tissue engineering strategies
• 3D-printed functional scaffolds for pathological tissue repair
• Cells and/or bioactive factors-loaded scaffolds for pathological tissue and/or organs repair
Tissue engineering technology is a multidisciplinary technology to construct a composite system of seed cells, scaffolds, and bioactive factors. This technology has achieved good results in repairing or replacing biological tissues in a healthy state. However, in the pathological microenvironment, it often leads to damaged function of seed cells, inactivation of bioactive factors, and abnormal degradation or damage of scaffolds. Targeting the local microenvironment specifically to different diseases and designing specific tissue engineering strategies to repair and replace tissue damage is an urgent problem to be solved.
This Research Topic focuses on basic and applied research that adopts advanced materials in the establishment and repair of the pathological microenvironment to restore the functions of tissues and/or organs. The topic welcomes, but is not limited to, Original Research, Reviews, and Mini Reviews in the following research areas:
• Design, development, and evaluation of novel pathological models in vitro and in vivo
• Pathological microenvironment models for tissue and/or organ repair
• Advanced materials target specific pathological microenvironments
• The interaction between pathological microenvironments and tissue engineering strategies
• 3D-printed functional scaffolds for pathological tissue repair
• Cells and/or bioactive factors-loaded scaffolds for pathological tissue and/or organs repair
