Editorial

23 January 2018

Editorial: Single-Domain Antibodies—Biology, Engineering and Emerging Applications

Kevin A. Henry

and

C. Roger MacKenzie

4,533 views

8 citations

Editors

Kevin A. Henry

National Research Council Canada (NRC)

Colin Roger MacKenzie

National Research Council Canada (NRC)

Impact

Technology Report

23 January 2018

A cDNA Immunization Strategy to Generate Nanobodies against Membrane Proteins in Native Conformation

Thomas Eden

, 8 more and

Friedrich Koch-Nolte

8,660 views

31 citations

Original Research

22 December 2017

Novel, Anti-hTNF-α Variable New Antigen Receptor Formats with Enhanced Neutralizing Potency and Multifunctionality, Generated for Therapeutic Development

Obinna C. Ubah

, 5 more and

Caroline J. Barelle

7,503 views

31 citations

Review

13 December 2017

Single-Domain Antibodies As Therapeutics against Human Viral Diseases

Yanling Wu

, 1 more and

Tianlei Ying

19,857 views

93 citations

Original Research

12 December 2017

Stability-Diversity Tradeoffs Impose Fundamental Constraints on Selection of Synthetic Human VH/VL Single-Domain Antibodies from In Vitro Display Libraries

Kevin A. Henry

, 7 more and

Jamshid Tanha

7,308 views

17 citations

Review

08 December 2017

Nanobodies As Novel Agents for Targeting Angiogenesis in Solid Cancers

Roghaye Arezumand

, 3 more and

Serge Muyldermans

10,566 views

54 citations

Perspective

20 November 2017

Camelid Single-Domain Antibodies: Historical Perspective and Future Outlook

Mehdi Arbabi-Ghahroudi

36,196 views

173 citations

Review

02 November 2017

Nanobody-Based Delivery Systems for Diagnosis and Targeted Tumor Therapy

Yaozhong Hu

, 1 more and

Serge Muyldermans

19,249 views

152 citations

Original Research

30 October 2017

A Novel Affinity Tag, ABTAG, and Its Application to the Affinity Screening of Single-Domain Antibodies Selected by Phage Display

Greg Hussack

, 6 more and

C. Roger MacKenzie

9,351 views

10 citations

Original Research

23 October 2017

In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties to Facilitate Clinical Development

John Steven

, 9 more and

Caroline Jane Barelle

9,721 views

39 citations

Perspective

12 October 2017

Antibody or Antibody Fragments: Implications for Molecular Imaging and Targeted Therapy of Solid Tumors

Katerina T. Xenaki

, 1 more and

Paul M. P. van Bergen en Henegouwen

24,608 views

222 citations

Original Research

02 October 2017

Unveiling a Drift Resistant Cryptotope within Marburgvirus Nucleoprotein Recognized by Llama Single-Domain Antibodies

John Anthony Garza

, 3 more and

Andrew Hayhurst

7,590 views

18 citations

Original Research

27 September 2017

Intracellular Crosslinking of Filoviral Nucleoproteins with Xintrabodies Restricts Viral Packaging

Tamarand Lee Darling

, 1 more and

Andrew Hayhurst

4,064 views

15 citations

Original Research

25 September 2017

Therapeutic Potential of Shark Anti-ICOSL VNAR Domains is Exemplified in a Murine Model of Autoimmune Non-Infectious Uveitis

Marina Kovaleva

, 3 more and

Andrew Porter

4,472 views

41 citations

Original Research

04 September 2017

Facile Affinity Maturation of Antibody Variable Domains Using Natural Diversity Mutagenesis

Kathryn E. Tiller

, 5 more and

Peter M. Tessier

14,954 views

54 citations

Perspective

01 September 2017

VHH-Based Bispecific Antibodies Targeting Cytokine Production

Maxim A. Nosenko

, 6 more and

Sergei A. Nedospasov

7,095 views

32 citations

Mini Review

24 August 2017

Under the Microscope: Single-Domain Antibodies for Live-Cell Imaging and Super-Resolution Microscopy

Bjoern Traenkle

and

Ulrich Rothbauer

18,118 views

104 citations

Review

21 August 2017

Single-Domain Antibodies As Versatile Affinity Reagents for Analytical and Diagnostic Applications

Gualberto Gonzalez-Sapienza

, 1 more and

Sofía Tabares-da Rosa

24,809 views

150 citations

Original Research

21 August 2017

Development and Characterization of a Camelid Single Domain Antibody–Urease Conjugate That Targets Vascular Endothelial Growth Factor Receptor 2

Baomin Tian

, 3 more and

Heman Chao

4,917 views

16 citations

Original Research

21 August 2017

Neutralization of Human Interleukin 23 by Multivalent Nanobodies Explained by the Structure of Cytokine–Nanobody Complex

Aline Desmyter

, 8 more and

Heidi Rommelaere

10,077 views

39 citations

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Single-Domain Antibodies: Biology, Engineering and Emerging Applications

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