Currently, musculoskeletal injuries, including injuries of the bone, articular cartilage, menisci, tendons, and ligaments, still provide an ongoing reconstructive and regenerative challenge in clinical work. To promote musculoskeletal regeneration and repair, numerous novel strategies have been developed in recent years, including the evolution of surgical techniques, biomaterials, and musculoskeletal tissue engineering. However, only a very limited number of technologies and biomaterials have been successfully translated into clinical applications. Therefore, there is still a high demand for the development of advanced biomaterials and methods that enhance the success of efforts to promote structural repair and functional regeneration of the musculoskeletal tissues, and eventually overcome challenges for their future clinical translation.
This Research Topic “Biofabrication Approaches for Musculoskeletal Regeneration and Repair” aims to present the major advances in the field of musculoskeletal tissue engineering and the recent progress of novel clinical techniques and strategies for musculoskeletal tissue repair and regeneration. The Research Topic will accept original papers and reviews on the array of novel bioengineering and nanotechnology, such as new biomaterials, biofabrication technologies, stem cell science, gene isolation and transfection, and other therapeutic approaches for the regeneration of musculoskeletal defects. In addition, clinical, biomechanical, and in vitro studies on innovative surgical techniques, pre-surgical models, and regenerative approaches to implants with musculoskeletal defects are also welcomed.
The topics and themes of this Research Topic will include, but are not limited to, the following:
• The creation of novel biomaterials for the regeneration of bone, cartilage, ligaments, and tendons;
• Novel molecular mechanism studies on musculoskeletal regeneration and repair;
• Novel surgical strategies developed for musculoskeletal repair or reconstruction;
• Novel animal models created for the efficient evaluation of pre-clinical treatment;
• Advanced application of mesenchymal stem cell (MSC)-mediated or cell-free approach (such as MSC-derived exosomes) for musculoskeletal tissue regeneration;
• Development of a translational therapeutic approach for potential clinical application.
Currently, musculoskeletal injuries, including injuries of the bone, articular cartilage, menisci, tendons, and ligaments, still provide an ongoing reconstructive and regenerative challenge in clinical work. To promote musculoskeletal regeneration and repair, numerous novel strategies have been developed in recent years, including the evolution of surgical techniques, biomaterials, and musculoskeletal tissue engineering. However, only a very limited number of technologies and biomaterials have been successfully translated into clinical applications. Therefore, there is still a high demand for the development of advanced biomaterials and methods that enhance the success of efforts to promote structural repair and functional regeneration of the musculoskeletal tissues, and eventually overcome challenges for their future clinical translation.
This Research Topic “Biofabrication Approaches for Musculoskeletal Regeneration and Repair” aims to present the major advances in the field of musculoskeletal tissue engineering and the recent progress of novel clinical techniques and strategies for musculoskeletal tissue repair and regeneration. The Research Topic will accept original papers and reviews on the array of novel bioengineering and nanotechnology, such as new biomaterials, biofabrication technologies, stem cell science, gene isolation and transfection, and other therapeutic approaches for the regeneration of musculoskeletal defects. In addition, clinical, biomechanical, and in vitro studies on innovative surgical techniques, pre-surgical models, and regenerative approaches to implants with musculoskeletal defects are also welcomed.
The topics and themes of this Research Topic will include, but are not limited to, the following:
• The creation of novel biomaterials for the regeneration of bone, cartilage, ligaments, and tendons;
• Novel molecular mechanism studies on musculoskeletal regeneration and repair;
• Novel surgical strategies developed for musculoskeletal repair or reconstruction;
• Novel animal models created for the efficient evaluation of pre-clinical treatment;
• Advanced application of mesenchymal stem cell (MSC)-mediated or cell-free approach (such as MSC-derived exosomes) for musculoskeletal tissue regeneration;
• Development of a translational therapeutic approach for potential clinical application.