About this Research Topic
The effects of a whole diet and multi-nutrient approaches, along with specific nutrients, show great promise to counteract the growing problem of age-related cognitive decline. However, there are still some questions regarding the role of diet in healthy aging, like the effect of the gut microbiome on the aging process and the development of new techniques including imaging measures of brain metabolomics, biomarkers, and metabolism. However; because of the serious challenges in nutrition research to improve neurological diseases, it is an urgent need for employing the outcomes of this matter in the clinical context. There are some promising initiatives in place, but more research is still needed to fully discover the mechanisms through which nutrition might enhance brain health across the lifespan of humans.
A healthy brain is strongly correlated with diet quality. Diet affects the development of neurological diseases and life expectancy, by altering the aging process. It has been shown that dietary ingredients could have serious impacts on mental health. A healthy diet enables the management and prevention of neurological diseases and aging. In addition, it is found that there is a relationship between an unhealthy diet and diminished cognitive function. Multiple factors contribute to neurodegenerative diseases, leading to a progressive loss of neuronal function in the brain and consequent cognitive dysfunction and motor neuron disorders. Inhibiting cognitive decline in neurodegenerative diseases like Parkinson's, Huntington's, and Alzheimer's diseases is possible with diets high in immune, neuroprotective, anti-inflammatory, antioxidant, antistress, antidepressant, factors, and senolytic activity. Furthermore, it influences the gut-brain axis by fostering a variety of gut microbes. This Research Topic focuses on dietary elements, natural substances, and medicinal plants that have the potential to show promise in the treatment of neurological diseases and for maintaining neural health during aging considering the significance of nutrition in the control of age-related neurological diseases.
This Research Topic collection welcomes the submission of articles (especially systematic reviews and meta-analyses) investigating the relationship between diet and age-related neurodegenerative disorders. The topics of interest include, but are not limited to, the following:
•Role of a healthy diet in the prevention of neurological disorders
•Effect of nutrition on aging and healthy longevity
•The relationship between nutrition and brain aging
•The mechanisms involved in the prevention of brain aging via diet ingredients
Keywords: neurodegeneration, aging, diet, gut-brain axis, nutrition
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