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About this Research Topic

Manuscript Submission Deadline 02 October 2023
Manuscript Extension Submission Deadline 02 November 2023

Research examining the neurobiological basis of learning and memory has been dominated, perhaps rightfully, by studies focusing on the hippocampus. Such studies have provided valuable information regarding hippocampal contributions to memory, including identifying the types of memories processed by the hippocampus and the time course of hippocampal involvement in memory retrieval. However, this focus on the hippocampus has, to a degree, overshadowed the important contributions that other related cortical regions make to learning and memory. Current research highlights the importance of bi-directional and collaborative inactions between cortical regions and the hippocampus in order to support learning and memory.

The goal of this special issue is to highlight recent research and theory focused on cortico-hippocampal contributions to learning and memory. This issue will focus on the importance of collaborative networks that rely on interactions among the hippocampus and cortical regions to support learning and memory. This research topic has the main goal to enhance knowledge regarding how cortico-hippocampal interactions give rise to learning and memory.
This Research Topic welcomes studies in animals and/or humans, and article types including: original research, systematic reviews, reviews, mini reviews and brief research reports. Themes to be covered in this Research Topic may include, but are not limited to:

- Direct manipulation of cortico-hippocampal circuits in learning and memory.
- Indirect tests of cortico-hippocampal circuits, such as local manipulation of a targeted brain region within a larger network / circuit
- Behavior tasks may include a variety of learning and memory task, including, emotional (fear conditioning or avoidance), spatial, or episodic tasks.

Professor Karyn Frick is a co-founder of, and shareholder in, Estrigenix Therapeutics, Inc., a company which aims to improve women's health by developing safe, clinically proven treatments for the mental and physical effects of menopause. She also serves as the company's Chief Scientific Officer.

Keywords: learning, memory, neocortex, hippocampus, conditioning


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Research examining the neurobiological basis of learning and memory has been dominated, perhaps rightfully, by studies focusing on the hippocampus. Such studies have provided valuable information regarding hippocampal contributions to memory, including identifying the types of memories processed by the hippocampus and the time course of hippocampal involvement in memory retrieval. However, this focus on the hippocampus has, to a degree, overshadowed the important contributions that other related cortical regions make to learning and memory. Current research highlights the importance of bi-directional and collaborative inactions between cortical regions and the hippocampus in order to support learning and memory.

The goal of this special issue is to highlight recent research and theory focused on cortico-hippocampal contributions to learning and memory. This issue will focus on the importance of collaborative networks that rely on interactions among the hippocampus and cortical regions to support learning and memory. This research topic has the main goal to enhance knowledge regarding how cortico-hippocampal interactions give rise to learning and memory.
This Research Topic welcomes studies in animals and/or humans, and article types including: original research, systematic reviews, reviews, mini reviews and brief research reports. Themes to be covered in this Research Topic may include, but are not limited to:

- Direct manipulation of cortico-hippocampal circuits in learning and memory.
- Indirect tests of cortico-hippocampal circuits, such as local manipulation of a targeted brain region within a larger network / circuit
- Behavior tasks may include a variety of learning and memory task, including, emotional (fear conditioning or avoidance), spatial, or episodic tasks.

Professor Karyn Frick is a co-founder of, and shareholder in, Estrigenix Therapeutics, Inc., a company which aims to improve women's health by developing safe, clinically proven treatments for the mental and physical effects of menopause. She also serves as the company's Chief Scientific Officer.

Keywords: learning, memory, neocortex, hippocampus, conditioning


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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