It is well-established that COVID-19 is a systemic disease. Besides the respiratory system, the virus can infect different extrapulmonary tissues, and this infection can determine histopathological and molecular changes that disrupt the normal functions of the organism. Neurologic disorders, abnormal glycemic control, gastrointestinal symptoms, and even endocrine dysfunctions belong to the spectrum of COVID-19. Although these symptoms can be limited to the acute phase of infection, a significant number of patients with COVID-19 experience prolonged sequelae, even for weeks or months. The scientific community and general public are already accustomed to the terminology “long COVID” which is used to define this post-acute disease manifestation, which mirrors the late consequences of the viral insult.
This Research Topic has the aim of highlighting the current knowledge and the reports of the extrapulmonary involvement of SARS-CoV-2 infection. A special focus will be given to:
- COVID-19 vaccine-associated immune thrombosis and thrombocytopenia (VITT)
- Herpes zoster emergence following mRNA COVID-19 vaccine
- Myocarditis and Pericarditis After Vaccination for COVID-19
- Autoimmune diseases triggered by SARS-CoV-2 vaccination
- Other COVID-19 vaccine-associated adverse effects
It is well-established that COVID-19 is a systemic disease. Besides the respiratory system, the virus can infect different extrapulmonary tissues, and this infection can determine histopathological and molecular changes that disrupt the normal functions of the organism. Neurologic disorders, abnormal glycemic control, gastrointestinal symptoms, and even endocrine dysfunctions belong to the spectrum of COVID-19. Although these symptoms can be limited to the acute phase of infection, a significant number of patients with COVID-19 experience prolonged sequelae, even for weeks or months. The scientific community and general public are already accustomed to the terminology “long COVID” which is used to define this post-acute disease manifestation, which mirrors the late consequences of the viral insult.
This Research Topic has the aim of highlighting the current knowledge and the reports of the extrapulmonary involvement of SARS-CoV-2 infection. A special focus will be given to:
- COVID-19 vaccine-associated immune thrombosis and thrombocytopenia (VITT)
- Herpes zoster emergence following mRNA COVID-19 vaccine
- Myocarditis and Pericarditis After Vaccination for COVID-19
- Autoimmune diseases triggered by SARS-CoV-2 vaccination
- Other COVID-19 vaccine-associated adverse effects