About this Research Topic
The problem that this Research Topic aims to address is the current limitations of cancer therapy, including the lack of specificity and high toxicity associated with traditional chemotherapy and radiation therapy. In recent years, there has been growing interest in the use of exosomes derived from stem cells (SC-EXOs) as a potential alternative or complementary approach to cancer therapy. SC-EXOs offer several advantages, including their ability to selectively target cancer cells and deliver therapeutic payloads with high efficiency, while minimizing damage to healthy tissues.
To achieve this, researchers are exploring various approaches for manipulating SC-EXOs, such as loading them with specific drugs or engineering them to target specific cancer cell types. Additionally, recent advances in technology have made it possible to produce SC-EXOs on a large scale, which is crucial for their potential clinical translation. However, there are still several challenges that need to be addressed, such as standardization of production methods, optimization of therapeutic efficacy, and ensuring safety and regulatory compliance.
Our Research Topic aims to disseminate recent advancements in the field of stem cell-derived exosomes for cancer therapy. We welcome original research articles, reviews, and other acceptable article types that focus on the following topics:
• Methods and protocols for manipulating stem cell-derived exosomes for cancer therapy.
• In vitro and in vivo studies of naturally occurring or manipulated stem cell-derived exosomes for cancer therapy.
• Development of quality control measures and guidelines for the production and evaluation of stem cell-derived exosomes as cancer therapeutics.
Keywords: Cancer, Stem cell, Exosome, Cell therapy, Translational medicine, In vitro study, In vivo study, In silico study, Clinical trial
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.