Editors

Tashinga E Bapiro

AstraZeneca (United Kingdom)

Wagdy Mohamed Eldehna

Faculty of Pharmacy, Kafrelsheikh University

Viviana di Giacomo

University of Studies G. d'Annunzio Chieti and Pescara

Impact

Original Research

27 February 2025

Discovery of highly potent and novel LSD1 inhibitors for the treatment of acute myeloid leukemia: structure-based virtual screening, molecular dynamics simulation, and biological evaluation

Ye Hong

, 8 more and

Yanming Zhang

1,129 views

0 citations

Original Research

21 February 2025

Adverse drug reactions to atezolizumab in combination with bevacizumab in hepatocellular carcinoma patients: an analysis of the food and drug administration adverse event reporting system database

Wanming He

, 4 more and

Xingxi Pan

1,729 views

0 citations

Case Report

04 February 2025

Long term survival of advanced hepatoid adenocarcinoma of lung secondary to idiopathic pulmonary fibrosis: a case report

Xiaoli Wang

, 4 more and

Qianqian Zhang

776 views

0 citations

Systematic Review

08 January 2025

Peritoneal chemotherapy delivery systems for ovarian cancer treatment: systematic review of animal models

Marcelo Simonsen

, 7 more and

Maria Aparecida Azevedo Koike Folgueira

1,228 views

0 citations

Original Research

03 January 2025

Synthesis, characterization, and computational evaluation of some synthesized xanthone derivatives: focus on kinase target network and biomedical properties

Wisam Taher Muslim

, 6 more and

Helgi B. Schiöth

2,051 views

0 citations

Original Research

12 November 2024

Efficacy and safety of regorafenib for the treatment of metastatic colorectal cancer in routine clinical practice: results from a Spanish hospital

Pilar Sotoca Rubio

, 13 more and

Belén de Frutos González

915 views

0 citations

Case Report

26 September 2024

A case report: deep and durable response to low-dose lenvatinib and tislelizumab in an elderly patient with advanced intrahepatic cholangiocarcinoma

Pei Zhang

, 4 more and

Dan Cao

1,118 views

0 citations

Original Research

21 August 2024

CAR-T therapy pulmonary adverse event profile: a pharmacovigilance study based on FAERS database (2017–2023)

Jing Shi

, 5 more and

Li Wu

2,069 views

0 citations

Case Report

13 August 2024

Case report: Pyrotinib and tegafur combined with radiotherapy achieved notable response in HER2-amplified rectal cancer with multiple metastases after multiline treatments

Peng Huang

, 1 more and

Xin Wang

982 views

1 citations

Review

18 July 2024

Nutrient vitamins enabled metabolic regulation of ferroptosis via reactive oxygen species biology

Junjie Wu

, 8 more and

Weiqi Wang

1,871 views

5 citations

Original Research

28 June 2024

Sugemalimab combined with chemotherapy for the treatment of advanced esophageal squamous cell carcinoma: a cost-effectiveness analysis

Hongfu Cai

, 1 more and

Zhiwei Zheng

1,065 views

1 citations

Original Research

28 June 2024

Structure-based screening of FDA-approved drugs identifies potential histone deacetylase 3 repurposed inhibitor: molecular docking and molecular dynamic simulation approaches

Anas Shamsi

, 2 more and

Moyad Shahwan

2,052 views

4 citations

Opinion

27 June 2024

Repurposing therapy of ibrexafungerp vulvovaginal candidiasis drugs as cancer therapeutics

Tedi Rustandi

, 7 more and

Faizatun Faizatun

1,596 views

0 citations

Case Report

17 June 2024

Niraparib for the treatment of metastatic ccRCC in a patient with CDK12 and RAD51C mutations: a case report

Xiaolong Yue

, 2 more and

Yue Li

1,389 views

1 citations

Case Report

20 May 2024

QL1604 combined with bevacizumab as an innovative first-line treatment for HCC patient with extensive metastasis who showed remarkable effect: a case report

Yanzhi Wan

, 1 more and

Hong Zhu

814 views

0 citations

Original Research

17 May 2024

Benserazide, a cystathionine beta-synthase (CBS) inhibitor, potentially enhances the anticancer effects of paclitaxel via inhibiting the S-sulfhydration of SIRT1 and the HIF1-α/VEGF pathway

Wei Zhao

, 6 more and

Tianxiao Wang

2,200 views

3 citations

Original Research

01 May 2024

Marine-derived EGFR inhibitors: novel compounds targeting breast cancer growth and drug resistance

Qi Li

, 4 more and

Tianfu Xu

1,687 views

4 citations

Original Research

08 April 2024

Activation of p53 signaling and regression of breast and prostate carcinoma cells by spirooxindole-benzimidazole small molecules

Assem Barakat

, 7 more and

Yaseen A. M. M. Elshaier

1,456 views

1 citations

Original Research

03 April 2024

Discovery of a novel natural compound, vitekwangin B, with ANO1 protein reduction properties and anticancer potential

Yohan Seo

, 11 more and

Joohan Woo

3,661 views

1 citations

Mini Review

07 March 2024

Article review: Brazilin as potential anticancer agent

Callista Najla Raptania

, 2 more and

Riezki Amalia

5,929 views

3 citations

Fetching...

Home Frontiers in Pharmacology…Experimental Pharmacology and Drug Discovery…Research Topics

Enjoyed this Research Topic?

Share it using

Drug Discovery in Cancer Research: Success Stories and Open Challenges

48.8K

views

186

authors

articles