Community Series in Reducing Adverse Effects of Cancer Immunotherapy: Volume II

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Community Series in Reducing Adverse Effects of Cancer Immunotherapy: Volume II

97.4K

views

130

authors

22

articles

Editorial

28 November 2025

Editorial: Community series in reducing adverse effects of cancer immunotherapy, volume II

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This Research Topic is the second volume of the “Reducing Adverse Effects of Cancer Immunotherapy” Community Series. Please see Volume I here.

Cancer immunotherapy has emerged as a promising treatment modality, offering hope for improved survival rates and outcomes in cancer patients. However, the adverse effects associated with cancer treatments, including immunotherapy, remain a significant challenge. These side effects, such as fatigue, stress, hair loss, pain, nausea, vomiting, anemia, and mucositis, can severely impact patients' quality of life and may lead to additional costs, morbidity, and even mortality. The complexity of managing these adverse effects is compounded by the potential need to reduce treatment doses, which can compromise therapeutic efficacy. Recent studies have highlighted the urgent need for innovative strategies to mitigate these side effects, ensuring that patients can maintain a better quality of life while undergoing treatment. Despite ongoing research, there remains a gap in effective solutions that can alleviate these adverse effects without compromising the treatment's effectiveness, underscoring the necessity for continued investigation in this field.

This research topic aims to explore and identify novel strategies and interventions that can reduce the adverse effects of cancer immunotherapy. By focusing on innovative treatment options and therapeutic or preventive alternatives, the goal is to enhance the tolerability of oncological treatments and improve the overall quality of life for cancer patients. This includes addressing specific questions related to the mechanisms underlying these side effects and testing hypotheses about potential interventions that could mitigate them.

To gather further insights in the realm of reducing adverse effects of cancer immunotherapy, we welcome articles addressing, but not limited to, the following themes:
- Development of new therapeutic strategies to alleviate side effects.
- Mechanistic studies on the causes of adverse effects in cancer immunotherapy.
- Clinical trials evaluating the efficacy of interventions aimed at reducing side effects.
- Translational research linking basic science findings to clinical applications.
- Reviews and perspectives on current challenges and future directions in managing treatment-related side effects.

This Research Topic is the second volume of the “Reducing Adverse Effects of Cancer Immunotherapy” Community Series. Please see Volume I here.

Cancer immunotherapy has emerged as a promising treatment modality, offering hope for improved survival rates and outcomes in cancer patients. However, the adverse effects associated with cancer treatments, including immunotherapy, remain a significant challenge. These side effects, such as fatigue, stress, hair loss, pain, nausea, vomiting, anemia, and mucositis, can severely impact patients' quality of life and may lead to additional costs, morbidity, and even mortality. The complexity of managing these adverse effects is compounded by the potential need to reduce treatment doses, which can compromise therapeutic efficacy. Recent studies have highlighted the urgent need for innovative strategies to mitigate these side effects, ensuring that patients can maintain a better quality of life while undergoing treatment. Despite ongoing research, there remains a gap in effective solutions that can alleviate these adverse effects without compromising the treatment's effectiveness, underscoring the necessity for continued investigation in this field.

This research topic aims to explore and identify novel strategies and interventions that can reduce the adverse effects of cancer immunotherapy. By focusing on innovative treatment options and therapeutic or preventive alternatives, the goal is to enhance the tolerability of oncological treatments and improve the overall quality of life for cancer patients. This includes addressing specific questions related to the mechanisms underlying these side effects and testing hypotheses about potential interventions that could mitigate them.

To gather further insights in the realm of reducing adverse effects of cancer immunotherapy, we welcome articles addressing, but not limited to, the following themes:
- Development of new therapeutic strategies to alleviate side effects.
- Mechanistic studies on the causes of adverse effects in cancer immunotherapy.
- Clinical trials evaluating the efficacy of interventions aimed at reducing side effects.
- Translational research linking basic science findings to clinical applications.
- Reviews and perspectives on current challenges and future directions in managing treatment-related side effects.

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Frontiers in Immunology

Inflammation, Cancer Immunity and Immunotherapy

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Frontiers in Oncology

Cancer Immunity and Immunotherapy

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