Plant-derived Therapeutics and Traditional Medicine: Innovations, Challenges, and Opportunities in Breast Cancer Treatment

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ORIGINAL RESEARCH

Published on 21 May 2025

Antiproliferative and pro-apoptotic effects of Pseudevernia furfuracea (L.) Zopf extract and its active component physodic acid via oxidative stress and DNA damage in breast cancer cells

Dominika Sebova
Simona Zilakova
Viktoria Medvecova
Michal Goga
Richard Frenak
Annamaria Bardelcikova
Andrej Mirossay
Ladislav Mirossay
Jan Mojzis
Martin Kello

doi 10.3389/fonc.2025.1557884

799 views

ORIGINAL RESEARCH

Published on 30 Apr 2025

Chemopreventive and therapeutic effects of Hippophae rhamnoides L. fruit peels evaluated in preclinical models of breast carcinoma

Dana Dvorska
Dominika Sebova
Karol Kajo
Andrea Kapinova
Emil Svajdlenka
Michal Goga
Richard Frenak
Jakub Treml
Sandra Mersakova
14 more
Peter Kubatka

doi 10.3389/fphar.2025.1561436

1,543 views

METHODS

Published on 25 Apr 2025

Mechanism of total saponins of Ranunculus ternatus Thunb. in treatment of breast cancer based on liquid chromatography–mass spectrometry and network analysis

Yuanxin Zhang
Shuo Nan
Wei Zhao
Haisheng Xie
Jinxin Miao
Mingsan Miao

doi 10.3389/fphar.2025.1506885

720 views

ORIGINAL RESEARCH

Published on 25 Apr 2025

Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway

Yingchao Wu
Liushan Chen
Dajin Pi
Jiaqi Cui
Yuqi Liang
Peng Wu
Mingzi Ouyang
Qian Zuo

doi 10.3389/fphar.2025.1532579

1,126 views

REVIEW

Published on 17 Jan 2025

Plant protein-derived anti-breast cancer peptides: sources, therapeutic approaches, mechanisms, and nanoparticle design

Deju Zhang
Ying Yuan
Qingdong Zeng
Juan Xiong
Yiming Gan
Kai Jiang
Ni Xie

doi 10.3389/fphar.2024.1468977

1,350 views
2 citations

ORIGINAL RESEARCH

Published on 14 Jan 2025

Cellulose nanofiber reinforced curcumin-infused calcium phosphate silicate cement for various bone-tissue engineering application

Xiu Guo Lu
Sha Li Meng
Qiu Jing Zhou
Tao Wu
Xing Tian Gong
Qiong Wu

doi 10.3389/fonc.2024.1516638

906 views
1 citation

REVIEW

Published on 08 Jan 2025

Kleinia (Asteraceae): comprehensive review of ethnomedicinal uses, phytochemical profiles, ethnopharmacological applications, and toxicological insights

Bantayehu Addis Tegegne
Tesfa Begashaw
Wubetu Yihunie Belay
Mengistie Kassahun Tariku
Tirsit Ketsela Zeleke
Mohammed Jemal
Mamaru Getinet
Agumas Alemu Alehegn
Abebe Dagne

doi 10.3389/fphar.2024.1469887

1,889 views

REVIEW

Published on 23 Oct 2024

Benign and malignant breast lesions in children and adolescents - diagnostic and therapeutic approach

Patrycja Sosnowska-Sienkiewicz
Danuta Januszkiewicz-Lewandowska
Przemysław Mańkowski

doi 10.3389/fped.2024.1417050

2,274 views
1 citation

ORIGINAL RESEARCH

Published on 27 Sep 2024

Formononetin triggers ferroptosis in triple-negative breast cancer cells by regulating the mTORC1/SREBP1/SCD1 pathway

Dong Xie
Yulang Jiang
Huan Wang
Lingyi Zhu
Shuangqin Huang
Sheng Liu
Weihong Zhang
Tian Li

doi 10.3389/fphar.2024.1441105

1,784 views
4 citations

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Ethnopharmacology
Pharmacology of Anti-Cancer Drugs

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Frontiers in Oncology
- Pharmacology of Anti-Cancer Drugs
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Articles

Antiproliferative and pro-apoptotic effects of Pseudevernia furfuracea (L.) Zopf extract and its active component physodic acid via oxidative stress and DNA damage in breast cancer cells

Chemopreventive and therapeutic effects of Hippophae rhamnoides L. fruit peels evaluated in preclinical models of breast carcinoma

Mechanism of total saponins of Ranunculus ternatus Thunb. in treatment of breast cancer based on liquid chromatography–mass spectrometry and network analysis

Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway

Plant protein-derived anti-breast cancer peptides: sources, therapeutic approaches, mechanisms, and nanoparticle design

Cellulose nanofiber reinforced curcumin-infused calcium phosphate silicate cement for various bone-tissue engineering application

Kleinia (Asteraceae): comprehensive review of ethnomedicinal uses, phytochemical profiles, ethnopharmacological applications, and toxicological insights

Benign and malignant breast lesions in children and adolescents - diagnostic and therapeutic approach

Formononetin triggers ferroptosis in triple-negative breast cancer cells by regulating the mTORC1/SREBP1/SCD1 pathway

Frontiers in Pharmacology

Ethnopharmacology

Pharmacology of Anti-Cancer Drugs

Participating Journals

Frontiers in Oncology

Pharmacology of Anti-Cancer Drugs