Krill oil is a popular food supplement as it comprises marine omega-3 fatty acids, phospholipids, choline, and astaxanthin. The omega-3 fatty acids are mostly bound to phospholipids, mainly phosphatidylcholine, while in fish oil omega-3 fatty acids are bound to triglycerides. Hence, krill oil is different from fish oil in terms of chemical composition. Furthermore, there is mounting evidence of nutritional differences as well, especially in animal models, krill oil tends to perform better than fish oil. There is increasing documentation that the phospholipid form of the omega-3 fatty acids enhances its efficacy. However, this may not be sufficient to explain the biological differences observed. Krill oil may in addition have a more profound effect on the cell membrane, cell signaling, and how the cell functions.
Krill oil is a package of essential nutrients. It is effectively absorbed and transferred to target tissues, where it replenishes cell membrane deficiencies and leads to positive health effects. What is needed is to clarify what krill oil does at a fundamental level and how this may lead to nutritional effects which are both unique and beneficial. The goal is to validate krill oil across many health conditions and diseases, thereby expanding the use of krill oil. This can be achieved by focusing on what krill oil does on a cellular level measuring relevant biomarkers using advanced chromatographic and biomolecular techniques. For example, investigating the downstream processes and mechanisms such as the effect on gene expression, effects on inflammation, lipid metabolism, and the endocannabinoid system.
In this Research Topic, we are looking for research on how krill oil modulates human health. We are of particular interest in receiving research on how krill oil affects selected biomarkers on human health at a cellular level and how this differentiates from comparative products. Investigating for differential effects on for example markers of inflammation, pain, mobility, disease activity measures in autoimmune diseases, metabolic syndrome, brain health, and heart health. We are seeking both advanced randomized clinical trials as well as informal open-label trials performed in humans.
Topic Editor Dr. Inge Bruheim is employed by Rimfrost Group AS. Topic Editor Prof. Stine Marie Ulven declares no competing interests with regard to the Research Topic subject.
Keywords:
Krill, Phospholipid, EPA, DHA, Astaxanthin, Choline, Inflammation, Metabolism, Diseases
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
Krill oil is a popular food supplement as it comprises marine omega-3 fatty acids, phospholipids, choline, and astaxanthin. The omega-3 fatty acids are mostly bound to phospholipids, mainly phosphatidylcholine, while in fish oil omega-3 fatty acids are bound to triglycerides. Hence, krill oil is different from fish oil in terms of chemical composition. Furthermore, there is mounting evidence of nutritional differences as well, especially in animal models, krill oil tends to perform better than fish oil. There is increasing documentation that the phospholipid form of the omega-3 fatty acids enhances its efficacy. However, this may not be sufficient to explain the biological differences observed. Krill oil may in addition have a more profound effect on the cell membrane, cell signaling, and how the cell functions.
Krill oil is a package of essential nutrients. It is effectively absorbed and transferred to target tissues, where it replenishes cell membrane deficiencies and leads to positive health effects. What is needed is to clarify what krill oil does at a fundamental level and how this may lead to nutritional effects which are both unique and beneficial. The goal is to validate krill oil across many health conditions and diseases, thereby expanding the use of krill oil. This can be achieved by focusing on what krill oil does on a cellular level measuring relevant biomarkers using advanced chromatographic and biomolecular techniques. For example, investigating the downstream processes and mechanisms such as the effect on gene expression, effects on inflammation, lipid metabolism, and the endocannabinoid system.
In this Research Topic, we are looking for research on how krill oil modulates human health. We are of particular interest in receiving research on how krill oil affects selected biomarkers on human health at a cellular level and how this differentiates from comparative products. Investigating for differential effects on for example markers of inflammation, pain, mobility, disease activity measures in autoimmune diseases, metabolic syndrome, brain health, and heart health. We are seeking both advanced randomized clinical trials as well as informal open-label trials performed in humans.
Topic Editor Dr. Inge Bruheim is employed by Rimfrost Group AS. Topic Editor Prof. Stine Marie Ulven declares no competing interests with regard to the Research Topic subject.
Keywords:
Krill, Phospholipid, EPA, DHA, Astaxanthin, Choline, Inflammation, Metabolism, Diseases
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.