Immune Response in Tuberculosis with Comorbidities or Coinfections

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ORIGINAL RESEARCH

Published on 19 May 2025

Latent tuberculosis coinfection in mild COVID-19 is associated with a distinct immune cell phenotype marked by enhanced cytotoxic degranulation and mitochondrial alterations

Carlos Peña-Bates
Lucero A. Ramón-Luing
Julio Flores-Gonzalez
Enrique Espinosa
María F. Martinez-Moreno
Karen Medina-Quero
Marco A. Vargas-Hernandez
Norma A. Téllez-Navarrete
Fernando M. Sosa-Gomez
2 more
Leslie Chavez-Galan

doi 10.3389/fimmu.2025.1566449

287 views

ORIGINAL RESEARCH

Published on 24 Mar 2025

Mutations in ace2 gene modulate cytokine levels and alter immune responses in Mycobacterium tuberculosis and SARS-CoV-2 co-infection: a Cameroonian cohort

Mary Ngongang Kameni
Eric Berenger Tchoupe
Severin Donald Kamdem
Nikhil Bhalla
Jean Paul Assam Assam
Arnaud Njuiget Tepa
Fuh Roger Neba
Ranjan Kumar Nanda
Anthony Afum-Adjei Awuah
1 more
Palmer Masumbe Netongo

doi 10.3389/fimmu.2025.1533213

1,188 views

REVIEW

Published on 03 Feb 2025

Management of tuberculosis risk, screening and preventive therapy in patients with chronic autoimmune arthritis undergoing biotechnological and targeted immunosuppressive agents

Andrea Picchianti-Diamanti
Alessandra Aiello
Chiara De Lorenzo
Giovanni Battista Migliori
Delia Goletti

doi 10.3389/fimmu.2025.1494283

2,378 views

ORIGINAL RESEARCH

Published on 17 Jan 2025

Assessing the effects of diabetes mellitus on the monocyte-to-lymphocyte ratio and the QuantiFERON-TB gold plus assays for tuberculosis treatment monitoring: a prospective cohort study

Paulo Ranaivomanana
Arimanitra Razafimahefa
Mame Ndiaye
Crisca Razafimahatratra
Haja Ramamonjisoa
Perlinot Herindrainy
Mamy Raherison
Antso Hasina Raherinandrasana
Julio Rakotonirina
2 more
Niaina Rakotosamimanana

doi 10.3389/fimmu.2024.1451046

996 views

ORIGINAL RESEARCH

Published on 14 Jan 2025

Coexistent anemia modulates systemic inflammation and exacerbates disease severity and adverse treatment outcomes in tuberculosis

Bindu Dasan
Saravanan Munisankar
Nathella Pavan Kumar
Kadar Moideen
Arul Nancy Pandiarajan
Sujatha Nott
Vijay Viswanathan
Sivakumar Shanmugam
Syed Hissar
2 more
Subash Babu

doi 10.3389/ftubr.2024.1462654

587 views

ORIGINAL RESEARCH

Published on 13 Jan 2025

Specific immune response to M. tuberculosis and ability to in vitro control mycobacterial replication are not impaired in subjects with immune-mediated inflammatory disease and tuberculosis infection

Chiara Farroni
Anna Maria Gerarda Altera
Andrea Salmi
Valentina Vanini
Gilda Cuzzi
Cecilia S. Lindestam Arlehamn
Alessandro Sette
Giovanni Delogu
Ivana Palucci
6 more
Elisa Petruccioli

doi 10.3389/fimmu.2024.1484143

1,072 views
1 citation

REVIEW

Published on 18 Dec 2024

Intersecting epidemics: deciphering the complexities of tuberculosis-diabetes comorbidity

Mariana Araujo-Pereira
Caian L. Vinhaes
Beatriz Barreto-Duarte
Klauss Villalva-Serra
Artur T. L. Queiroz
Bruno B. Andrade

doi 10.3389/ftubr.2024.1487793

475 views

ORIGINAL RESEARCH

Published on 06 Nov 2024

Macrophage-derived extracellular vesicles from Ascaris lumbricoides antigen exposure enhance Mycobacterium tuberculosis growth control, reduce IL-1β, and contain miR-342-5p, miR-516b-5p, and miR-570-3p that regulate PI3K/AKT and MAPK signaling pathways

Giggil Pushpamithran
Robert Blomgran

doi 10.3389/fimmu.2024.1454881

1,840 views

ORIGINAL RESEARCH

Published on 04 Oct 2024

Impaired Mycobacterium tuberculosis-specific T-cell memory phenotypes and functional profiles among adults with type 2 diabetes mellitus in Uganda

Phillip Ssekamatte
Rose Nabatanzi
Diana Sitenda
Marjorie Nakibuule
Bernard Ssentalo Bagaya
Davis Kibirige
Andrew Peter Kyazze
David Patrick Kateete
Obondo James Sande
2 more
Irene Andia Biraro

doi 10.3389/fimmu.2024.1480739

1,679 views
3 citations

ORIGINAL RESEARCH

Published on 29 Aug 2024

Cytokine and chemokine profiles in pulmonary tuberculosis with pre-diabetes

Anuradha Rajamanickam
Sanaadhan P. Kothandaraman
Nathella Pavan Kumar
Vijay Viswanathan
Sivakumar Shanmugam
Syed Hissar
Sujatha Nott
Hardy Kornfeld
Subash Babu

doi 10.3389/fimmu.2024.1447161

1,382 views
1 citation

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Frontiers in Immunology

Microbial Immunology

Participating Journals

Frontiers in Tuberculosis
- Immunological Basis of Tuberculosis

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Articles

Latent tuberculosis coinfection in mild COVID-19 is associated with a distinct immune cell phenotype marked by enhanced cytotoxic degranulation and mitochondrial alterations

Mutations in ace2 gene modulate cytokine levels and alter immune responses in Mycobacterium tuberculosis and SARS-CoV-2 co-infection: a Cameroonian cohort

Management of tuberculosis risk, screening and preventive therapy in patients with chronic autoimmune arthritis undergoing biotechnological and targeted immunosuppressive agents

Assessing the effects of diabetes mellitus on the monocyte-to-lymphocyte ratio and the QuantiFERON-TB gold plus assays for tuberculosis treatment monitoring: a prospective cohort study

Coexistent anemia modulates systemic inflammation and exacerbates disease severity and adverse treatment outcomes in tuberculosis

Specific immune response to M. tuberculosis and ability to in vitro control mycobacterial replication are not impaired in subjects with immune-mediated inflammatory disease and tuberculosis infection

Intersecting epidemics: deciphering the complexities of tuberculosis-diabetes comorbidity

Macrophage-derived extracellular vesicles from Ascaris lumbricoides antigen exposure enhance Mycobacterium tuberculosis growth control, reduce IL-1β, and contain miR-342-5p, miR-516b-5p, and miR-570-3p that regulate PI3K/AKT and MAPK signaling pathways

Impaired Mycobacterium tuberculosis-specific T-cell memory phenotypes and functional profiles among adults with type 2 diabetes mellitus in Uganda

Cytokine and chemokine profiles in pulmonary tuberculosis with pre-diabetes

Frontiers in Immunology

Microbial Immunology

Participating Journals

Frontiers in Tuberculosis

Immunological Basis of Tuberculosis