The field of microbiome research has increasingly highlighted the significant connections between the oral and gut microbiomes and their collective impact on host health. Recent studies have shown that the oral microbiome, traditionally associated with oral health, also plays a crucial role in systemic health through the oral-gut axis. This axis suggests that microorganisms and their metabolites can translocate from the oral cavity to the gastrointestinal tract, potentially inducing dysbiosis and intestinal inflammation. Despite the growing body of evidence, there remains a substantial gap in our understanding of the specific mechanisms and interactions at play. Current research is often hampered by variability in methodologies, such as sample collection, storage, and DNA extraction, which can influence the observed microbial composition. Addressing these gaps is essential for developing targeted therapeutic strategies and improving overall health outcomes.
This research topic aims to investigate the interconnectedness between the oral microbiome and the gut microbiome. While considerable attention has been given to understanding these microbiomes independently, there is a growing recognition of the extensive bidirectional relationship between these two systems. By investigating and unraveling the intricate link between the oral and gut microbiomes, we hope this research can inform effective therapeutic strategies and fuel comprehensive healthcare discussions and practices. This topic will contribute significantly to the body of knowledge surrounding oral health, gut health, and the interplay between the two.
To gather further insights into the oral-gut microbiome axis, we welcome articles addressing, but not limited to, the following themes:
- Oral-Gut Microbiome Axis: An Overview - Providing an in-depth review of existing knowledge regarding key interactions and communication between oral and gut microbiomes.
- Microbial Migration: From Oral to Gut - Chromatographic analyses demonstrate the dynamic movements of microbiota from oral to gut, transforming and adapting to their new environments.
- Impact on Health and Disease - Delving into the role of oral and gut microbiome interactions in susceptibility to and development of various health conditions such as inflammatory bowel diseases, obesity, cancer, cardiovascular diseases, and neurological disorders.
- Influence of Diet on the Oral-Gut Microbiota Link - Exploring how nutritional habits could mediate the oral-gut microbiota axis impacting health and disease.
- Therapeutic Implications and Interventions - Considering potential strategies to manipulate and optimize the oral and gut microbiome for better health outcomes.
Topic Editor Zhangran Chen is now employed by Shenzhen Wedge Microbiology Research Co. Ltd. All other topic editors declare no competing interests with regard to the Research Topic subject.
The field of microbiome research has increasingly highlighted the significant connections between the oral and gut microbiomes and their collective impact on host health. Recent studies have shown that the oral microbiome, traditionally associated with oral health, also plays a crucial role in systemic health through the oral-gut axis. This axis suggests that microorganisms and their metabolites can translocate from the oral cavity to the gastrointestinal tract, potentially inducing dysbiosis and intestinal inflammation. Despite the growing body of evidence, there remains a substantial gap in our understanding of the specific mechanisms and interactions at play. Current research is often hampered by variability in methodologies, such as sample collection, storage, and DNA extraction, which can influence the observed microbial composition. Addressing these gaps is essential for developing targeted therapeutic strategies and improving overall health outcomes.
This research topic aims to investigate the interconnectedness between the oral microbiome and the gut microbiome. While considerable attention has been given to understanding these microbiomes independently, there is a growing recognition of the extensive bidirectional relationship between these two systems. By investigating and unraveling the intricate link between the oral and gut microbiomes, we hope this research can inform effective therapeutic strategies and fuel comprehensive healthcare discussions and practices. This topic will contribute significantly to the body of knowledge surrounding oral health, gut health, and the interplay between the two.
To gather further insights into the oral-gut microbiome axis, we welcome articles addressing, but not limited to, the following themes:
- Oral-Gut Microbiome Axis: An Overview - Providing an in-depth review of existing knowledge regarding key interactions and communication between oral and gut microbiomes.
- Microbial Migration: From Oral to Gut - Chromatographic analyses demonstrate the dynamic movements of microbiota from oral to gut, transforming and adapting to their new environments.
- Impact on Health and Disease - Delving into the role of oral and gut microbiome interactions in susceptibility to and development of various health conditions such as inflammatory bowel diseases, obesity, cancer, cardiovascular diseases, and neurological disorders.
- Influence of Diet on the Oral-Gut Microbiota Link - Exploring how nutritional habits could mediate the oral-gut microbiota axis impacting health and disease.
- Therapeutic Implications and Interventions - Considering potential strategies to manipulate and optimize the oral and gut microbiome for better health outcomes.
Topic Editor Zhangran Chen is now employed by Shenzhen Wedge Microbiology Research Co. Ltd. All other topic editors declare no competing interests with regard to the Research Topic subject.