Research Topic

Yeast programmed cell death and ageing

About this Research Topic

Similarly to metazoans, yeast cells can exhibit several characteristics of apoptosis, including chromatin condensation, DNA breakage, flipping of phosphatidylserine to the outer membrane, production of reactive oxygen species, and cytochrome c release from the mitochondria. Yeast programmed cell death has ...

Similarly to metazoans, yeast cells can exhibit several characteristics of apoptosis, including chromatin condensation, DNA breakage, flipping of phosphatidylserine to the outer membrane, production of reactive oxygen species, and cytochrome c release from the mitochondria. Yeast programmed cell death has been shown to occur in response to a variety of exogenous stimuli, such as oxidative stress, exposure to acetic acid and expression of mammalian pro-apoptotic proteins. This program is also inherent to the yeast life cycle, as aged mother cells and cells exposed to pheromone also display an apoptotic and necrotic phenotype. We are interested in manuscripts enhancing our understanding on PCD and its deregulation relevant in human pathologies and ageing. These include the identification of previously uncharacterized proteins involved in PCD and ageing, studies involving humanized yeasts, and yeast-based screens for drug discovery.


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Recent Articles

Loading..

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Topic Editors

Loading..

Submission Deadlines

Submission closed.

Participating Journals

Loading..

Topic Editors

Loading..

Submission Deadlines

Submission closed.

Participating Journals

Loading..
Loading..

total views article views article downloads topic views

}
 
Top countries
Top referring sites
Loading..

Comments

Loading..

Add a comment

Add comment
Back to top