About this Research Topic
The development of methods to block arbovirus transmission from the vector may be effective at ceasing arthropod-to-human infection since the current recommendation to prevent these viral infections is to decrease contact with mosquitoes. Additionally, improving our understanding of epidemiology and ecology will also help develop measures to reduce virus spread. In order to better study mammalian and insect host responses to infection, a number of genetic tools are available, such as Drosophila, mosquito, and tick insect models, recombinant viruses, mouse models, and bioinformatics tools.
The studies described in this Research Topic will illustrate host responses to infection using mammalian and insect models, identify critical signaling nodes of the innate immune response, and discuss virus transmission from insect to mammal or among infected hosts. Taken together, these studies will elucidate means of decreasing infections in human populations and provide potential targets for future study and therapeutic design.
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Keywords: West Nile virus, Dengue virus, Zika virus, innate immunity, epidemiology, ecology, Powassan virus, Heartland virus, arthropod, Drosophila, tick, mosquito, immune response, therapeutics
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