The pathogenic Yersiniae – advances in the understanding of physiology and virulence

123.5K

views

71

authors

17

articles

The pathogenic Yersiniae – advances in the understanding of physiology and virulence

123.5K

views

71

authors

17

articles

Editorial

12 September 2013

The pathogenic Yersiniae—advances in the understanding of physiology and virulence

Matthew S. Francis

4,426 views

6 citations

Editors

1

Matthew S Francis

Umeå University

Impact

About

From early studies of the plague causing agent through to comparatively more recent research defining aspects of the type III secretion mechanism, pathogenic Yersinia have served as an inventive model organism for researchers seeking to understand the complexities of bacteria-host cell interactions. In fact, seminal studies on Yersinia virulence mechanisms contributed to the emergence and recognition of the research field – cellular microbiology. Researching Yersinia infection biology continues to bring to light novel discoveries. Assortments of Yersinia whole genome sequencing projects are providing unparalleled insight into bacterial pathogen evolution and environmental adaptation. This is enabling researchers to identify and define more fascinating virulence and/or survival mechanisms that advance and expand existing perceptions of bacterial-host encounters. Current research is also beginning to bring to light how the pathogenic Yersiniae respond to physicochemical environmental cues to spatially and temporally control their armoury of customized virulence/survival factors. This Research Topic is therefore focused on presenting and summarizing new developments in Yersinia pathogenicity through highlighting cutting-edge studies on the Yersinia-host cell interaction and the network of regulatory control mechanisms that define this outcome. It will also endeavour to address how such findings might influence selection of potential targets for the design and development of anti-Yersinia therapeutic drugs and vaccines, as well as identify translational studies that involve unique and rewarding cooperation between diverse disciplines.

From early studies of the plague causing agent through to comparatively more recent research defining aspects of the type III secretion mechanism, pathogenic Yersinia have served as an inventive model organism for researchers seeking to understand the complexities of bacteria-host cell interactions. In fact, seminal studies on Yersinia virulence mechanisms contributed to the emergence and recognition of the research field – cellular microbiology. Researching Yersinia infection biology continues to bring to light novel discoveries. Assortments of Yersinia whole genome sequencing projects are providing unparalleled insight into bacterial pathogen evolution and environmental adaptation. This is enabling researchers to identify and define more fascinating virulence and/or survival mechanisms that advance and expand existing perceptions of bacterial-host encounters. Current research is also beginning to bring to light how the pathogenic Yersiniae respond to physicochemical environmental cues to spatially and temporally control their armoury of customized virulence/survival factors. This Research Topic is therefore focused on presenting and summarizing new developments in Yersinia pathogenicity through highlighting cutting-edge studies on the Yersinia-host cell interaction and the network of regulatory control mechanisms that define this outcome. It will also endeavour to address how such findings might influence selection of potential targets for the design and development of anti-Yersinia therapeutic drugs and vaccines, as well as identify translational studies that involve unique and rewarding cooperation between diverse disciplines.

Download ebook

Share

Editors

Matthew S Francis

Umeå University

Impact

123,512 Total views

93,488 Article views

25,140 Article downloads

4,884 Topic views

Published In

Journal Thumbnail

Frontiers in Cellular and Infection Microbiology

Clinical Microbiology, Bacteria and Host, Molecular Bacterial Pathogenesis, Cellular and Infection Microbiology Archive

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Suggest a topic