Zoonotic diseases, infections transmitted between animals and humans, are a significant concern in public health due to their ability to cause severe, potentially fatal illnesses or, conversely, present asymptomatically in hosts. These diseases constitute approximately 60% of all human diseases and 75% of emerging infectious diseases, highlighting their considerable impact on global health paradigms. While some progress has been made in understanding these pathogens, significant gaps remain, particularly in how these diseases emerge, evolve, and spread across species. This Research Topic aims to enhance understanding of zoonotic diseases by examining their pathogenesis, molecular evolution, transmission dynamics, and host-pathogen interactions. Research will also focus on innovative prevention and control strategies to address these pressing public health challenges. The ultimate goal is to fill existing knowledge gaps, particularly in neglected diseases, and improve management strategies for infections that can cross species barriers, thereby safeguarding global health. To delve deeper into the intricacies of zoonotic diseases and magnify their broader health implications, this Research Topic will cover a range of themes, including: - Prevalence, host specificity, and the epidemiology of zoonotic diseases - Advanced methods in genomic, transcriptomic, and proteomic analysis to track pathogen evolution - The impact of zoonotic diseases on host health and the mechanisms of the disease - In-depth analysis of host-pathogen interactions, focusing on aspects like phages and antimicrobial resistance - Cutting-edge prevention and control techniques for managing zoonotic diseases By targeting these key areas, this Research Topic aims to promote a comprehensive understanding and innovative solutions for managing zoonotic diseases effectively.
Zoonotic diseases, infections transmitted between animals and humans, are a significant concern in public health due to their ability to cause severe, potentially fatal illnesses or, conversely, present asymptomatically in hosts. These diseases constitute approximately 60% of all human diseases and 75% of emerging infectious diseases, highlighting their considerable impact on global health paradigms. While some progress has been made in understanding these pathogens, significant gaps remain, particularly in how these diseases emerge, evolve, and spread across species. This Research Topic aims to enhance understanding of zoonotic diseases by examining their pathogenesis, molecular evolution, transmission dynamics, and host-pathogen interactions. Research will also focus on innovative prevention and control strategies to address these pressing public health challenges. The ultimate goal is to fill existing knowledge gaps, particularly in neglected diseases, and improve management strategies for infections that can cross species barriers, thereby safeguarding global health. To delve deeper into the intricacies of zoonotic diseases and magnify their broader health implications, this Research Topic will cover a range of themes, including: - Prevalence, host specificity, and the epidemiology of zoonotic diseases - Advanced methods in genomic, transcriptomic, and proteomic analysis to track pathogen evolution - The impact of zoonotic diseases on host health and the mechanisms of the disease - In-depth analysis of host-pathogen interactions, focusing on aspects like phages and antimicrobial resistance - Cutting-edge prevention and control techniques for managing zoonotic diseases By targeting these key areas, this Research Topic aims to promote a comprehensive understanding and innovative solutions for managing zoonotic diseases effectively.