About this Research Topic
In recent years, numerous studies have addressed these fundamental issues, revealing sophisticated mechanisms engaged by the immune system to maintain oral mucosal homeostasis and to combat various immunological insults. Some of these studies have identified novel immunological mechanisms, emphasizing the uniqueness of the oral immune system and the necessity to further investigate its functions.
This Research Topic aims to provide a comprehensive overview of current research on the function of the oral immune system at steady state, and how it is modulated during disease, ageing and cancer. We welcome the submission of Original Research, Review and Mini-Review articles that cover, but are not limited to, the following topics:
1. Characterization of the oral mucosa immune system.
2. Maintenance of oral mucosal homeostasis.
3. Immunological functions of the oral epithelium.
4. Systemic effects associated with the oral mucosa.
5. Inflammation-induced oral diseases (e.g. periodontitis and peri-implantitis).
6. Tolerance induction in the oral mucosa.
7. Aging of the oral mucosa immune system.
8. Immune surveillance and oral cancers.
Keywords: Oral mucosa, Oral immunity, Oral cancer, Oral epithelium
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.