About this Research Topic
These effectors must be specifically recognized, selected and transported by the secretion apparatus, and thus specific signals and cognate receptors have evolved. As a consequence, the components, organization, architecture and mechanism of action of these different secretion systems are highly variable. Finally, some of these secretion systems have also hijacked host factors, such as chaperone, to facilitate their assembly. The biogenesis of these macromolecular machines is sophisticated and, in most cases, not yet understood. However, recent developments in electron microscopy to image large complexes and in fluorescence microscopy to dissect the dynamics of these complexes have provided important insights.
This topic collection welcomes up-to-date descriptions of each transport system and their putative roles in the pathogenicity of common bacteria species.
Keywords: Bacteria, Secretion, Membrane, Transport, Protein Complex, Pathogen
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