Research Topic

Applications of Fluorescence in Surgery and Interventional Diagnostics

About this Research Topic

Light has a dual nature of being a photon and an electromagnetic wave. Important properties of light include transport of energy, dispersion into spectrum, refraction, interference, diffraction, and polarization. Surgeons mainly rely on the visual information gained by the retinal detection of the light from the surgical light sources, such as overhead, endoscope or microscope lamps, reflected from the patient tissues. Surgical imaging technologies that use advanced properties of light such as fluorescence to guide surgical procedures are becoming increasingly popular and effective. Advanced light imaging technologies augment the surgeon’s or interventionist’s vision by providing a magnified microscopic view of the surgical details and tissue properties down to the cellular level, including highlighting specific molecular signals of tissue, identifying hidden lesions under the tissue surface, showing blood flow through vessels and much more. Research techniques that employ fundamental light properties beyond the limits of human eye for surgical aids and interventional diagnostics have grown substantially and have significant potential to shape the future of surgery and medical treatment. Frontiers in Surgery would serve as the platform for a collection of articles to provide a comprehensive state-of-the-art update and systematization of these cutting edge technologies, accumulate evidence for their utility, and to present original recent advancements in this field.


This Research Topic welcomes surgeons, medical interventionists, pathologists, and researchers to publish their experience and research to improve intraoperative diagnosis, surgical guidance, workflow and outcomes, and other medical diagnostic or treatment interventions by using advanced fluorescence techniques, including specific fluorescence labeling, Raman spectroscopy, and reflectance microscopy for in vivo disease detection. This Research Topic will seek to communicate and advance these new techniques in an intersection of surgical, medical, and research specialties.


Keywords: Fluorescence guided surgery, endoscopy, endomicroscopy, reflectance, Raman spectroscopy


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Light has a dual nature of being a photon and an electromagnetic wave. Important properties of light include transport of energy, dispersion into spectrum, refraction, interference, diffraction, and polarization. Surgeons mainly rely on the visual information gained by the retinal detection of the light from the surgical light sources, such as overhead, endoscope or microscope lamps, reflected from the patient tissues. Surgical imaging technologies that use advanced properties of light such as fluorescence to guide surgical procedures are becoming increasingly popular and effective. Advanced light imaging technologies augment the surgeon’s or interventionist’s vision by providing a magnified microscopic view of the surgical details and tissue properties down to the cellular level, including highlighting specific molecular signals of tissue, identifying hidden lesions under the tissue surface, showing blood flow through vessels and much more. Research techniques that employ fundamental light properties beyond the limits of human eye for surgical aids and interventional diagnostics have grown substantially and have significant potential to shape the future of surgery and medical treatment. Frontiers in Surgery would serve as the platform for a collection of articles to provide a comprehensive state-of-the-art update and systematization of these cutting edge technologies, accumulate evidence for their utility, and to present original recent advancements in this field.


This Research Topic welcomes surgeons, medical interventionists, pathologists, and researchers to publish their experience and research to improve intraoperative diagnosis, surgical guidance, workflow and outcomes, and other medical diagnostic or treatment interventions by using advanced fluorescence techniques, including specific fluorescence labeling, Raman spectroscopy, and reflectance microscopy for in vivo disease detection. This Research Topic will seek to communicate and advance these new techniques in an intersection of surgical, medical, and research specialties.


Keywords: Fluorescence guided surgery, endoscopy, endomicroscopy, reflectance, Raman spectroscopy


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

06 January 2019 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

06 January 2019 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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