Research Topic

Antifungal Active Peptides and Proteins to Overcome Pesticide- and Drug-Resistance of Pathogenic Fungi

  • Submission closed.

About this Research Topic

Fungi are known as emerging destructive pathogens of agriculturally important plants, causing billions of Euros to be lost every year. In addition, they pose severe risks to human health by contaminating food products with mycotoxins. The application of medically related antifungal drugs in agriculture as ...

Fungi are known as emerging destructive pathogens of agriculturally important plants, causing billions of Euros to be lost every year. In addition, they pose severe risks to human health by contaminating food products with mycotoxins. The application of medically related antifungal drugs in agriculture as fungicides has triggered the development of resistance mechanisms and has resulted in promoting environmental reservoirs for drug-resistant human pathogens. In spite of the increasing number of life-threatening fungal infections with high mortality rates, caused by drug-resistant strains, and the fact that the prolonged antifungal therapies can seriously damage the host’s organs, new studies concerning the development of fast and safely applicable antifungal strategies are still neglected by the pharmaceutical industry and in medicine. With this considered, there is a substantial demand for the development of new and safely applicable antifungal strategies to prevent and treat fungal infections that threaten human welfare.

The already intensively studied antifungal peptides and proteins, show high fungal-selectivity and antimicrobial efficacy and provide a fundamental new and feasible base to address the global antifungal challenge. The knowledge about their efficacy, antifungal mechanism and structure is continuously expanding; but the available information about their fungal-specific targets is still limited. The present Research Topic goal is to collect cutting-edge research contributions which summarize the current knowledge on these aspects of the antifungal active peptides and proteins as well as their potential application in agriculture and medicine.

This Research Topic welcomes original research articles, reviews or mini reviews focusing on isolation, characterization, structure, mode of action, phylogeny, and potential agricultural or medical application of antifungal active natural or synthetic peptides and proteins.


Keywords: Fungal Infection, Antifungal Peptide, Antifungal Protein, Agriculture, Medicine


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Recent Articles

Loading..

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Topic Editors

Loading..

Submission Deadlines

Submission closed.

Participating Journals

Loading..

Topic Editors

Loading..

Submission Deadlines

Submission closed.

Participating Journals

Loading..
Loading..

total views article views article downloads topic views

}
 
Top countries
Top referring sites
Loading..

Comments

Loading..

Add a comment

Add comment
Back to top