About this Research Topic
N-of-1 RCTs and observational studies are well-suited to complement, strengthen, and generate advances in precision medicine, patient-centred healthcare, and personalised health. Since 2015, the number of N-of-1 articles has doubled annually.
Similarly, digital health is an exploding field, with over 1,000 studies registered on clinicaltrials.gov.
Digital health, and digital therapeutics in particular, complement N-of-1 RCTs and observational studies by providing relevant individualized health data from, for example, worn sensors, implants, regular lab assays, or -omics sequencing. Such data can be compared to population-health databases to target a patient’s strongest possible treatment option (as in cancer-risk studies) and, in turn, inform the design of an N-of-1 RCT to evaluate it.
Digital health data can also be continuously monitored during the study itself and used to help tailor a treatment to the needs and preferences of patients in real time.
This Research Topic will cover digital health applications, delivery, and analysis of N-of-1 RCTs and observational studies (including self-studies) in any health discipline.
The focus is on:
- mobile health (mHealth) and applications (apps)
- wearable devices, sensors and implants,
- real-time tracking, data analytics and online registries,
- patient experience of digital health and mobile health, patients as collaborators in personalised medicine, self-tracking in citizen science, etc.
The articles can be original research, methodology pieces, opinion pieces, reviews, systematic reviews, protocols, short reports, or case studies.
Topic Editor Dr Eric Daza is Senior Statistician at Clarify Health Solutions. All other Topic Editors declare no competing interests with regards to the Research Topic subject.
Keywords: data analytics, implants, personalized health, trials, sensors, real-time tracking, mobile health, N-of-1, RCT, digital health, individualized research, citizen science
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.