Research Topic

Advances and Challenges of Carrier Architectures for Bioactive Delivery Systems

About this Research Topic

Bioactives with unique functional properties of hypoglycemic, hypolipidemic, antidiabetic, antiinflamatory, antimicrobial, and antioxidant are of great and growing interest due to their enormous potential in food, nutraceuticals, medicine, cosmetics and agricultural chemicals industry. However, the commercial application of bioactive is currently limited because of their poor solubility, instability and susceptibility when exposed to light, heat, oxygen, acid and alkaline conditions. Furthermore, low and inconsistent bioavailability and efficacy have hampered them from commercialization and large-scale applications. Therefore, it is greatly important and highly desirable to develop innovative and high-performance protection and delivery systems to overcome these challenges. Recently, the development of efficient food-grade materials has drawn tremendous research attention since the increasing demands for biocompatibility, biodegradability and reduction of environmental impact. Despite the existing progress, this field still faces many challenges, for example: more diverse source of environmentally-friendly materials to build delivery cargos, delivery systems design with multi-functionality, facile and low manufacture cost fabrication methods, alongside, the promising analytical characterization of bioavailability, etc.

This Research Topic is to provide a central venue for researchers with interest in bioactives and nutraceuticals delivery systems. Most articles published will aims to highlight talented achievements in all areas of delivery systems, covering their preparation, fabrication, characterization and applications. Intensive experimental and theoretical investigations on novel nanostructures (nanoemulsion, nanohydrogel, nanocomplex, nanofiber and nanoparticle) designed for various bioactive ingredients have been performed to expand our fundamental understanding on delivery vehicles.

This Research Topic will accept the submission of Original Research, Review and Perspective articles from fundamental research to applied research. Manuscripts need to focus on carrier materials and characterization to be in the scope for this Research Topic. Manuscripts that only cover carrier applications and functionality are not within the scope. Major topics can include, but are not limited to:

• Chemical and process engineering of selected materials applied for bioactive delivery system from natural and sustainable sources
• The structural design of functional delivery vehicles and the fundamental investigation
• The innovative/facile strategies for construction/fabrication carriers with desirable properties
• The physical and chemical characterizations of architectures of bulk phases and interfaces of delivery systems
• The performance assessment in industrial applications, i.e. pharmacodynamic and pharmacokinetic aspects
• The future challenges and opportunities in novel delivery vehicles


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Bioactives with unique functional properties of hypoglycemic, hypolipidemic, antidiabetic, antiinflamatory, antimicrobial, and antioxidant are of great and growing interest due to their enormous potential in food, nutraceuticals, medicine, cosmetics and agricultural chemicals industry. However, the commercial application of bioactive is currently limited because of their poor solubility, instability and susceptibility when exposed to light, heat, oxygen, acid and alkaline conditions. Furthermore, low and inconsistent bioavailability and efficacy have hampered them from commercialization and large-scale applications. Therefore, it is greatly important and highly desirable to develop innovative and high-performance protection and delivery systems to overcome these challenges. Recently, the development of efficient food-grade materials has drawn tremendous research attention since the increasing demands for biocompatibility, biodegradability and reduction of environmental impact. Despite the existing progress, this field still faces many challenges, for example: more diverse source of environmentally-friendly materials to build delivery cargos, delivery systems design with multi-functionality, facile and low manufacture cost fabrication methods, alongside, the promising analytical characterization of bioavailability, etc.

This Research Topic is to provide a central venue for researchers with interest in bioactives and nutraceuticals delivery systems. Most articles published will aims to highlight talented achievements in all areas of delivery systems, covering their preparation, fabrication, characterization and applications. Intensive experimental and theoretical investigations on novel nanostructures (nanoemulsion, nanohydrogel, nanocomplex, nanofiber and nanoparticle) designed for various bioactive ingredients have been performed to expand our fundamental understanding on delivery vehicles.

This Research Topic will accept the submission of Original Research, Review and Perspective articles from fundamental research to applied research. Manuscripts need to focus on carrier materials and characterization to be in the scope for this Research Topic. Manuscripts that only cover carrier applications and functionality are not within the scope. Major topics can include, but are not limited to:

• Chemical and process engineering of selected materials applied for bioactive delivery system from natural and sustainable sources
• The structural design of functional delivery vehicles and the fundamental investigation
• The innovative/facile strategies for construction/fabrication carriers with desirable properties
• The physical and chemical characterizations of architectures of bulk phases and interfaces of delivery systems
• The performance assessment in industrial applications, i.e. pharmacodynamic and pharmacokinetic aspects
• The future challenges and opportunities in novel delivery vehicles


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

11 March 2020 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

11 March 2020 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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