About this Research Topic
The chemical structures of organic small molecules can be controlled and easily modified by a variety of supramolecular ensembles through covalent bonding. The introduction of small organic molecules to supramolecular ensembles will promote the development of new chemical tools or techniques to study biological systems, which will facilitate the investigation of cells or organism in vitro and in vivo. It will also pave the way for developing new sensing techniques that are easy to perform and low cost, as well as various drug carriers for biomedical applications.
The introduction of small organic molecules such as photo-responsive, electronic-responsive, and magnetic-responsive organic groups into the surface of supramolecular ensembles will greatly improve the property of the ensembles and motivate the development of new chemical tools and techniques for addressing some specific and complex biological problems. Through this Research topic, we want to provide a platform to increase the readers' and researchers’ understanding of design and construction of small organic modified supramolecular ensembles and to exhibit the superiority of these systems in biosensing and therapy. Original Research and Review articles covering the following topics are welcome:
• Small organic modified supramolecular ensembles for biological sensing for applications such as the sensing of specific signaling molecules in biological systems and macro-biomolecules, subcellular imaging, and discrimination of cells.
• Small organic molecules modified luminescence ensembles for biosensing, including new small organic molecules-based photoluminescence probes, chemiluminescence probes, and electrochemical sensors, etc.
• Multi-functional small organic molecules modified magnetic nanoprobes.
• Small organic modified supramolecular ensembles as diagnostic and therapeutic agents for the diagnosis, treatment, and prevention of disease.
• Other novel small organic molecules modified supramolecular ensembles are also welcome.
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