About this Research Topic
Human craniofacial morphology includes several distinct facial structures that contain enormous variation. The human face comprises a collection of multifactorial complex traits, with genetic factors and environmental factors playing key roles in its growth and development throughout life. The craniofacial growth and development, including muscles, bones and teeth are an intricate process that requires several signaling pathways with elaborate tissue interactions and molecular mechanisms that control craniofacial morphogenesis. Craniofacial development is complex and involves the ectoderm, mesoderm, and endoderm germ layers. In the past decades, researchers have been studying the aspects and factors involved in the craniofacial growth and development, as well as the etiology of many craniofacial conditions, using different methods and techniques. Whereas the etiology of many craniofacial development alterations and pathological conditions became well-established, the etiology of other disorders are still poorly explored and remains a largely unknown.
This Research Topic aims to provide an opportunity for researchers and clinicians from different perspectives and areas to discuss recent advances in the understanding of craniofacial growth and development, with particular focus on craniofacial disorders. In addition, we also aim to provide updated information regarding the etiological factors and risk factors involved in the development and establishment of the alterations and pathologies that affect the craniofacial complex. Different areas, such as developmental biology, human genetics, craniofacial syndromes, cleft lip and palate, and dental research, will come together in this article collection.
We welcome articles as Original Research, Case Reports, Reviews, Systematic Reviews and Mini Reviews that investigate and discuss the following topics:
• Developmental aspects of craniofacial disorders
• Developmental aspects of the normal craniofacial growth and development
• Craniofacial syndromes
• Craniofacial genetics
• Etiologic factors associated with cleft lip and/or palate
• Etiologic factors associated with dental developmental disorders
• Oral diseases
• Oral and dental genetics
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.