About this Research Topic
This Research Topic aims to provide a comprehensive and state of the art overview of different mechanisms that regulate chromatin and therefore the transcriptional status of the cells during the processes of development, differentiation, transdifferentiation and iPS cell reprogramming.
We welcome the submission of Original Research, Review and Mini-Review articles that cover recent and current research on the topic of mechanisms regulating chromatin in cell fate decisions. These mechanisms cover, but are not limited to the following topics:
• Chromatin regulation during organ development and organoid culture.
• DNA (hydroxy)methylation dynamics during early embryo development and iPS cell reprogramming.
• 3-D chromatin regulation during iPS cell reprogramming and pluripotency states.
• Regulatory RNAs in pluripotency establishment and maintenance.
• Role of genomic imprinting in pluripotency maintenance.
• Chromatin dynamics during normal and malignant hematopoietic cell fate decisions.
• Chromatin regulation during neural cell fate specification.
• Metabolism, chromatin and cell fate decisions.
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.