Gastrointestinal Tumor Heterogeneity and Related Anti-Cancer Strategies

71.2K

views

111

authors

17

articles

Gastrointestinal Tumor Heterogeneity and Related Anti-Cancer Strategies

71.2K

views

111

authors

17

articles

Editorial

11 April 2022

Editorial: Gastrointestinal Tumor Heterogeneity and Related Anti-Cancer Strategies

Rui Liao

,

Yu-Jun Shi

,

Michael D. Chuong

and

Ju Cao

1,687 views

2 citations

Editors

3

RUI LIAO

First Affiliated Hospital of Chongqing Medical University

YUJUN SHI

West China Hospital, Sichuan University

Ju Cao

First Affiliated Hospital of Chongqing Medical University

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Genomic profiling has revealed the heterogeneity of gastrointestinal tumors, and the combination of inter-patient heterogeneity and intra-tumor heterogeneity was identified as a determining factor of tumor development. Molecular heterogeneity at multiple levels including genomics, epigenomics, transcriptomics, and microenvironment features conferring each patient variation in the response to anti-cancer therapies should be considered. Due to the heterogeneity of gastrointestinal cancers associated with different clinical biometrics, the prognosis of each patient is different. Therefore, more novel and effective anti-cancer therapeutic algorithms should be discussed to selected subsets of gastrointestinal tumors.

This Research Topic aims to provide a comprehensive overview of recent advances in the association between tumor heterogeneity and related anti-cancer therapies for gastrointestinal cancer. We welcome the submission of Review and Original Research articles covering, but not limited to, the following topics:

• Novel molecular mechanism research on the association between heterogeneity and related anti-cancer therapies for gastrointestinal tumors including gastric, colorectal, liver, pancreas, bile duct, and esophageal tumors.
• Novel clinical research focus on anti-cancer strategies derived from tumor heterogeneity studies for gastrointestinal cancer
• Novel therapeutic targets derived from tumor heterogeneity studies for gastrointestinal cancer
• Novel special heterogeneity biomarker to predict the anti-cancer treatment response and prognosis of gastrointestinal cancer

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Editors

RUI LIAO

First Affiliated Hospital of Chongqing Medical University

YUJUN SHI

West China Hospital, Sichuan University

Ju Cao

First Affiliated Hospital of Chongqing Medical University

Impact

71,188 Total views

47,242 Article views

22,778 Article downloads

1,168 Topic views

Published In

Frontiers in Oncology

Gastrointestinal Cancers: Gastric and Esophageal Cancers

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