Frontiers in Oncology | Gastrointestinal Cancers: Gastric and Esophageal Cancers

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Journal notices

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Advancing Excellence in Thoracic Oncology: Breakthroughs and Impactful Discoveries

Curated by Giuseppe Giaccone (Cornell) and Sharon Pine (Univ. of Colorado), this collection showcases key advances in thoracic oncology: cancer biology, diagnostics, treatments, biomarkers, translational insights, early detection, and clinical care.

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Research Spotlight: Mechanisms and Technologies in Cancer Epigenetics

A tour of how DNA methylation, histone marks, chromatin remodeling, and non-coding RNAs shape tumors, plus tools like single-cell and multi-omics profiling, spatial epigenomics, long-read sequencing, and CRISPR-based epigenome editing.

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ESMO AI and Digital Oncology Congress 2025 in Berlin

We will attend the ESMO AI and Digital Oncology Congress in Berlin, 12–14 November 2025. Clinicians, researchers, and health leaders will share practical work to improve cancer diagnosis and care. We look forward to seeing you there.

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Editor’s Pick: ERα and GPER in Therapy Resistance

From receptor biology to resistance, this review charts ERα/ERβ and GPER signaling, ESR1 hotspot mutations that stabilize agonist states and fuel endocrine resistance, and new therapies aimed at ERα mutants and GPER.

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"From Virtual to Reality: the Future of Surgery" Congress, Treviso 2025

We are proud to sponsor a surgery-focused congress in Treviso, led by our Surgical Oncology Specialty Chief Editor, Dr. Francesco Giovinazzo. The program highlights advances in surgical oncology, minimally invasive care, robotics, AI, and AR.

Gastrointestinal Cancers: Gastric and Esophageal Cancers

Submit your research

Author guidelines

Editor guidelines

Peer review

Publishing fees

Journal notices

Advancing Excellence in Thoracic Oncology: Breakthroughs and Impactful Discoveries

Research Spotlight: Mechanisms and Technologies in Cancer Epigenetics

ESMO AI and Digital Oncology Congress 2025 in Berlin

Editor’s Pick: ERα and GPER in Therapy Resistance

"From Virtual to Reality: the Future of Surgery" Congress, Treviso 2025

Editors

liang qiao

ziad awad

abbes belkhiri

alberto biondi

Articles

Case report: Preliminary experience with organ-preserving treatment for locally advanced esophageal cancer in the immunotherapy era: a case series of four patients

Predictive Value of Neutrophil-to-Lymphocyte Ratio (NLR), Platelet-to-Lymphocyte Ratio (PLR), and Monocyte-to-Lymphocyte Ratio (MLR) for Three-Year Survival in Patients with Early Esophageal Cancer Undergoing Endoscopic Submucosal Dissection

Construction of a preoperative prehabilitation program for elderly esophageal cancer patients

The Identification of LA-Tumor Associated Macrophages in Immune Modulation via Amyloid-beta Precursor Protein/CD74 Signal Pathway in Gastric Cancer: A Predictive Module and Machine Learning

Research Topics

16 Years with Frontiers in Oncology: Celebrating Excellence and Innovation in Cancer Research

Innovative Pathological Approaches for Poorly Cohesive Gastric Cancer

Insights into Gastrointestinal Cancer Metastasis from Preclinical Models

Targeting Antigen Presentation and Protein Quality Control Pathways to Enhance Tumor Immunity in Gastro-Intestinal Cancers