Frontiers in Oncology

Original Research

Published on 04 Aug 2025

A proof-of-concept study of personalized dosimetry for targeted radioligand therapy using pre-treatment diagnostic dynamic PET/CT and Monte Carlo simulation

in Radiation Oncology

Thanh Tai Duong
Danny De Sarno
Hatim Fakir
Glenn Bauman
Martin Martinov
Rowan M. Thomson
Ting-Yim Lee

Frontiers in Oncology

doi 10.3389/fonc.2025.1600821

276 views

Original Research

Published on 04 Aug 2025

Individualization of clinical target volume delineation in eccentric nasopharyngeal carcinoma: a prospective comparative study

in Head and Neck Cancer

Yunrui Song
Yuwei Wang
Mengqi Yang
Xinhao Yu
Mengze Li
Bin Long
Xiaolei Shu
Xin Zhang
Feng Wang
Chencheng Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1587764

145 views

Mini Review

Published on 04 Aug 2025

Mapping the clinical trial landscape of multiple primary lung cancer in the era of precision oncology: persistent exclusion and design limitations hamper evidence-based treatment development

in Thoracic Oncology

Jianwei Shi
Linchuan Liang
Yushun Gao

Frontiers in Oncology

doi 10.3389/fonc.2025.1642062

204 views

Technology and Code

Published on 04 Aug 2025

A structure-based tool to interpret the significance of kinase mutations in clinical next generation sequencing in cancer

in Cancer Molecular Targets and Therapeutics

Amith Rangarajan
Ilona Sviezhentseva
Emma Gunderson
Yana Pikman
Matthew P. Jacobson
Beth Apsel Winger

Frontiers in Oncology

doi 10.3389/fonc.2025.1599389

160 views

Original Research

Published on 04 Aug 2025

Effects of immersive virtual therapy on psychological and physical wellbeing in women with breast cancer at different stages of disease and treatment conditions: an experimental comparative study

in Breast Cancer

Oliver Czech
Rafal Matkowski
Jakub Skórniak
Iwona Malicka

Frontiers in Oncology

doi 10.3389/fonc.2025.1581604

159 views

Original Research

Published on 04 Aug 2025

Integrating network pharmacology and transcriptomics to identify solasonine’s anti-osteosarcoma targets and experimental validation

in Pharmacology of Anti-Cancer Drugs

Daihao Wei
Minyu Li
Dawei Chu
Jiandang Shi

Frontiers in Oncology

doi 10.3389/fonc.2025.1614058

129 views

Systematic Review

Published on 04 Aug 2025

Systematic literature review of real-world evidence on overall survival in cancer patients before and after the approval of anti-PD-(L)1 therapy

in Cancer Immunity and Immunotherapy

Dweeti Nayak
Katherine G. Akers
Andrew M. Frederickson
Yves P.V. Mbous
Raquel Aguiar-Ibáñez

Frontiers in Oncology

doi 10.3389/fonc.2025.1615795

200 views

Original Research

Published on 04 Aug 2025

A four-gene signature identified by integrated transcriptomic analysis for differential diagnosis and prognosis of uterine smooth muscle tumors

in Gynecological Oncology

Huiyi Hu
Yuanqun Chen
Bo Hong
Jia Liu
Yuchen Jiang
Zhiying Yu
Zhi-Jie Xiao
Jing Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1591875

139 views

Original Research

Published on 04 Aug 2025

Relationship between immunohistochemical markers and clinical pathological variables in clear cell renal cell carcinoma

in Genitourinary Oncology

Pengshuai Liu
Junli Wei
Shubo Chen

Frontiers in Oncology

doi 10.3389/fonc.2025.1580024

141 views

Case Report

Published on 04 Aug 2025

Metastatic colon adenocarcinoma to the gingiva treated with spatial fractionation radiotherapy: a case report

in Radiation Oncology

Xinyi Liu
Ke Xu
Quan Yao
Jian Fang
Weiyi Zhou
Jinyi Lang

Frontiers in Oncology

doi 10.3389/fonc.2025.1580430

165 views

Systematic Review

Published on 04 Aug 2025

Umbrella review of photodynamic therapy for cancer: efficacy, safety, and clinical applications

in Cancer Molecular Targets and Therapeutics

Hanhan Chen
Honglin Li
Hui-Jie Li
Zhen Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1528314

213 views

Case Report

Published on 04 Aug 2025

Case Report: Epstein-Barr virus negative lymphoepithelioma-like cholangiocarcinoma: a rare tumor that deserves further exploration. Report of a case with distinct genomic and clinical features

in Gastrointestinal Cancers: Hepato Pancreatic Biliary Cancers

Salvatore Corallo
Chiara Milani
Alessandro Vanoli
Anna Gallotti
Anna Pagani
Francesco Serra
Marcello Maestri
Valentina Ravetta
Angioletta Lasagna
Paolo Pedrazzoli

Frontiers in Oncology

doi 10.3389/fonc.2025.1620328

255 views

Mini Review

Published on 04 Aug 2025

Cardiac toxicity and intervention strategies during thoracic cancer radiotherapy

in Radiation Oncology

Youjin Kong
Chao Yang
Lingling Xie
Yan Zhao
Zheng Rong
Xinbin Zhou
Wei Mao

Frontiers in Oncology

doi 10.3389/fonc.2025.1638035

187 views

Case Report

Accepted on 01 Aug 2025

Sequential PTCD and Biliary Seed Stent Combined with Targeted-Immunotherapy for Advanced Pancreatic Cancer with Malignant Obstructive Jaundice: A Multidisciplinary Approach

in Surgical Oncology

Weijun Li
Guoyang Sun
Rui Zhu
Pindong Li
Li Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1649080

238 views

Original Research

Accepted on 01 Aug 2025

NFIA-dependent upregulation of SMC4 promotes metastasis and metabolic reprogramming in glioma

in Neuro-Oncology and Neurosurgical Oncology

Guoyin Li
Yukui Zhao
Yubo He
Zhaoqiang Qian
Xiaoyan Li
Zewen Song
Zhiqiang Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1624370

124 views

Original Research

Accepted on 01 Aug 2025

Predictive Role of MGMT and IDH Status in the Efficacy of Bevacizumab for High-Grade Glioma: A Retrospective Study

in Neuro-Oncology and Neurosurgical Oncology

Bai xuexue
Yan Chengrui
Wenbin Ma
Feng ming
Wu Chao

Frontiers in Oncology

doi 10.3389/fonc.2025.1634892

130 views