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Scope
This section focuses on the investigation of tumorigenesis, prevention, early detection and treatment of colorectal neoplasia, with a particular interest in multidisciplinary research to support clinical applications of biological advances.
There are special considerations for submission to this section and authors are kindly encouraged to consult them in full by clicking "Read More" below.
Scope
The Gastrointestinal Cancers: Colorectal Cancers section aims at offering a wide and comprehensive approach to investigations concerning tumorigenesis, prevention, early detection and treatment of colorectal neoplasia. Even though the molecular machinery triggering and sustaining colorectal carcinogenesis and the morphogenetic pathways leading to cancer is, at least in part, well-established, knowledge has only been incompletely translated to the single patient care and population-based interventions, in spite of the technological novelties in endoscopy and imaging of colorectal tumors and their tailored treatments.
The ultimate effort of the section is, therefore, to support multidisciplinary research in order to speed up clinical applications of biological advances. For these reasons this section specifically welcomes contributions on the following topics:
- Genetic epidemiology and cancer determinant identification
- Molecular, genetic and morphological biomarkers of tumor progression
- Cancer chemo-prevention and delay
- Screening programs and cancer prevention trials
- Imaging and molecular imaging
- Endoscopic identification and treatment of early neoplasia
- Integrated treatments of advanced cancer
- Genetic syndromes in colorectal cancers
- Drug development Including gene therapy, stem cell therapy, immunotherapy and small molecules
While we welcome meta-analyses and descriptive studies (including those submitted as Original Research), these should be based on rigorous statistical methods or systematic reviews, and must bring new insights into the mechanisms of carcinogenesis. Furthermore, manuscripts focusing on cancer risk factors and stratification are not in scope for this section and should be submitted to Cancer Epidemiology and Prevention of Frontiers in Oncology.
In silico studies must be validated with a cell line study.
Submissions that are surgical in nature are not in scope for this section and should be submitted to the Surgical Oncology Section of Frontiers in Oncology.
Case Reports should include correlative data and expand the current knowledge on the pathophysiological and clinical manifestations of cancer while discussing the cellular and molecular levels of the disease.
Indexed in: PubMed, PubMed Central (PMC), Scopus, Web of Science Science Citation Index Expanded (SCIE), Google Scholar, DOAJ, CrossRef, Chemical Abstracts Service (CAS), CLOCKSS
Gastrointestinal Cancers: Colorectal Cancer welcomes submissions of the following article types: Clinical Trial, Correction, Editorial, General Commentary, Hypothesis and Theory, Methods, Mini Review, Opinion, Original Research, Perspective, Review, Specialty Grand Challenge, Systematic Review and Technology and Code.
All manuscripts must be submitted directly to the section Gastrointestinal Cancers: Colorectal Cancer, where they are peer-reviewed by the Associate and Review Editors of the specialty section.
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