Frontiers in Oncology | Gastrointestinal Cancers: Colorectal Cancer

Case Report

Published on 03 Dec 2025

Case Report: T-Dxd plus bevacizumab in a patient with brain metastases from rectal cancer with HER2 amplification

in Gastrointestinal Cancers: Colorectal Cancer

Yanan Jia
Xueqin Li
Huisheng Chen
Lisha Wu
Yinduo Zeng
Tao Qin

Frontiers in Oncology

doi 10.3389/fonc.2025.1714422

Review

Published on 03 Dec 2025

Neoadjuvant therapy for pMMR/MSS locally advanced rectal cancer in the immunotherapy era: current landscape and future perspectives

in Gastrointestinal Cancers: Colorectal Cancer

Benish Farooq
Xingyu Li
Sa Xiao
Xiaojun Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1719642

240 views

Review

Published on 03 Dec 2025

Microbiota-host metabolism reprogramming in colorectal cancer: from pathogenesis to precision therapies

in Gastrointestinal Cancers: Colorectal Cancer

Chengxu Guo
Caixia Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1713614

106 views

Original Research

Accepted on 02 Dec 2025

Global burden of Colorectal cancer from 1990 to 2021: a systematic analysis from the Global Burden of Disease Study 2021

in Gastrointestinal Cancers: Colorectal Cancer

Xue Chen
Rui Tian
Ze Chen
Longfang Quan
Shaosheng Bei

Frontiers in Oncology

Correction

Accepted on 30 Nov 2025

Correction: Multiomics Analyses of Human Colorectal Cancer Reveal Changes in Mitochondrial Metabolism Associated with Chemotherapy Resistance

in Gastrointestinal Cancers: Colorectal Cancer

Wei Zheng
Shiyi Chen
Qian Li

Frontiers in Oncology

Case Report

Accepted on 30 Nov 2025

Masquerading Doughnut: A Case of Misdiagnosed Ileocecal Tumor-Induced Intussusception

in Gastrointestinal Cancers: Colorectal Cancer

Guolin Zhang
Chuchu Xu
Renjun Zhu
Qingfeng Dai
Guangen Xu

Frontiers in Oncology

Original Research

Accepted on 30 Nov 2025

Poor nutritional status based on controlling nutritional status (CONUT) score and nutritional risk index (NRI) may be related to the occurrence of complications after laparoscopic treatment in patients with gastrointestinal tumors aged no more than 60 years

in Gastrointestinal Cancers: Colorectal Cancer

Zhiwang Li
Xueyong Deng
Lv Ye
Chengkun Yang

Frontiers in Oncology

Mini Review

Published on 28 Nov 2025

Advances in colorectal cancer screening: technological innovations, guideline discrepancies, and individualized strategies

in Gastrointestinal Cancers: Colorectal Cancer

Li Tang
Xiaoyong Zhao
Guohong Wang
Jiehao Huang
Mu Zhang
Wei Xu

Frontiers in Oncology

doi 10.3389/fonc.2025.1723546

375 views

Systematic Review

Accepted on 27 Nov 2025

Association between triglyceride-glucose index and risk of colorectal carcinogenesis: A meta-analysis of observational studies

in Gastrointestinal Cancers: Colorectal Cancer

Lichao Wang
Yuxuan Lin
Yonghe Liao
Jinhai Shen

Frontiers in Oncology

Original Research

Published on 27 Nov 2025

Identification of a signature gene set for oxaliplatin sensitivity prediction in colorectal cancer

in Gastrointestinal Cancers: Colorectal Cancer

Xiaopeng Zhan
Xinyue Li
Yimin Chu
Ying Xu
Fengli Zhou
Ji Li
Daming Yang
Changping Hu
Haixia Peng
Zhaoxia Wu

Frontiers in Oncology

doi 10.3389/fonc.2025.1701328

457 views

Original Research

Accepted on 25 Nov 2025

A two-stage deep learning prediction system for colon cancer microsatellite instability(MSI) status using CT images

in Gastrointestinal Cancers: Colorectal Cancer

Songlin Cui
Xin Xiong
Xudong Yang
Jianfeng He
Tao Shen

Frontiers in Oncology

Original Research

Accepted on 25 Nov 2025

Citywide Community-Based Colorectal Cancer Screening in Urban Shanghai: Age and Sex Variations in Risk Mitigation from 1973 to 2020

in Gastrointestinal Cancers: Colorectal Cancer

Mengyin Wu
Yangming Gong
Chunxiao Wu
Peng Peng
Chen Lei
Li Qi
Liang Shi
Yongmei Xiang
Jianming Dou
Yi Pang

Frontiers in Oncology

Original Research

Published on 25 Nov 2025

The role of TMEM59L in colorectal cancer progression and its interaction with the TGF-β/Smad pathway

in Gastrointestinal Cancers: Colorectal Cancer

Hongjie Yang
Jiafei Liu
Peishi Jiang
Yi Sun
Lingyi Chen
Siwei Zhu

Frontiers in Oncology

doi 10.3389/fonc.2025.1674849

353 views

Case Report

Published on 24 Nov 2025

Complete remission of advanced MSI-H rectal cancer in a young patient treated with nivolumab: a case report and critical appraisal of the literature

in Gastrointestinal Cancers: Colorectal Cancer

Marian Liberko
Renata Soumarova

Frontiers in Oncology

doi 10.3389/fonc.2025.1680308

514 views

Original Research

Published on 24 Nov 2025

Global, regional and national burden of colorectal cancer and its risk factors, 1990–2021: a systematic analysis for the GBD 2021

in Gastrointestinal Cancers: Colorectal Cancer

Xuan Zeng
Jibo Wang
Ning Liu
Long Chen
Liang Liang
Li Zhuo
Xiaoyong Zhang
Mao Lin

Frontiers in Oncology

doi 10.3389/fonc.2025.1673341

421 views

Original Research

Accepted on 21 Nov 2025

A large-scale study integrating CEA and tumor deposits to evaluate prognosis in colon cancer patients

in Gastrointestinal Cancers: Colorectal Cancer

Ya'Nan Fan
Yun Sun
Xiaojie Hu
Li-Fei Zhang
Jiantao Dong
Fei Liu
Zhiqiang Zhang
Jianhui Cai

Frontiers in Oncology

151 views