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The use of medical imaging has substantially increased over the past decade, thanks to the technological advancements evident from the dramatic improvement in the sensitivity and spatial resolution of imaging modalities. Cardiovascular imaging has been at a crossroad with respect to the technological ...

The use of medical imaging has substantially increased over the past decade, thanks to the technological advancements evident from the dramatic improvement in the sensitivity and spatial resolution of imaging modalities. Cardiovascular imaging has been at a crossroad with respect to the technological advances, with a shift in focus from single-modality diagnosis to an integrated multimodality approach that can provide comprehensive assessments of morphology, pathophysiology and biology of disease and can stratify the patient risk, and guide therapy for cardiovascular disease.

Due to the wide inter-subject variability in cardiovascular anatomy and pathophysiology, it is necessary to design personalized treatment plans that would highly benefit from clinical imaging technologies. The remarkable advances in medical imaging, have motivated the development of new tools that can augment the power of medical imaging to provide information beyond anatomy-based diagnosis. In addition to providing comprehensive diagnostic information, some of these tools can even predict effectiveness of interventions by allowing systematic testing of possible clinical interventions, and thereby they enable personalized interventions.

This Research Topic covers the novel tools that augment the power of medical imaging to provide quantitative information about cardiovascular disease beyond conventional diagnosis. The following themes are included in the scope:

• Advanced image processing for diagnosis, monitoring and prediction of cardiovascular disease
• Advanced signal processing for diagnosis, monitoring and prediction of cardiovascular disease
• Imaged-based experimental biomechanics for prediction of effects of treatments of cardiovascular dis-eases
• Advances in image-guided interventions
• Integration of medical imaging and computational modelling for intervention predictions
• Personalization of treatment through image-based hypothesis testing

Important Note: All submissions/contributions to this Research Topic must be in line with the scope of the journal/section they are submitted to. While authors are encouraged to draw from other disciplines to enrich their papers where relevant, they must ensure papers fall within the scope of the journal/section, as expressed in its mission statement.

Dr. Zahra Motamed holds patents on valvular, vascular and ventricular diseases and treatment. Dr. Edelman holds numerous patents on vascular/ cardiovascular therapeutics, injury, imaging, and sensing. Dr. Bluestein holds patents on platelet activation, microfluidics, and prosthetic heart valve design, and also stands as the Founder and CSO of startup company Polynova Cardiovascular Inc. Dr. Del Alamo holds patents on cardiovascular function, disorders and risk. All other Topic Editors declare no potential conflicts of interest with regard to the Research Topic subject.

Keywords: Cardiovascular Disease, Diagnostic Method, Medical Imaging, Monitoring Tools, Fluid Dynamics, Blood Flow


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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