About this Research Topic
Bacteria belonging to the genus Acinetobacter are glucose non-fermentative Gram-negative coccobacilli that are a frequent cause of health-care associated infections and hospital outbreaks. A. baumannii and the emergent species of A. baumannii (Ab) group other than A. baumannii such as A. nosocomialis, A. pittii, A. seifertii, and A. lactucae/dijkshoorniae are the most clinically relevant species. Global epidemiology of A. baumannii showed A. baumannii had a clonal population structure dominated by two major international clonal lineages and few additional epidemic clones. The most successful Acinetobacter clones show resistance to a broad range of antimicrobials and disinfectants and share virulence features such as biofilm formation on abiotic surfaces, resistance to desiccation and adherence to epithelial cells, which contribute to their survival in the hospital environment and spread among patients.
This Research Topic is intended to collect original updates on the drug resistance, global epidemiology and Virulence of Acinetobacter. The genomic epidemiology of A. baumannii and the emergent species of A. baumannii (Ab) group will be investigated on a global scale. The molecular mechanisms of antimicrobial resistance, adaptation and biofilm persistence of Acinetobacter will be analyzed. The novel strategies to control Acinetobacter spread in the environment and infection in the human host will be elucidated.
Manuscripts will primarily be selected based on novelty of research findings and scientific quality. We invite contributors to submit original research papers, reviews, short notes, or commentaries in the following primary areas:
• New or changing patterns in the epidemiology of A. baumannii and of the emergent species of A. baumannii group;
• Molecular determinants, genetic and genomic elements of antimicrobial resistance in Acinetobacter;
• Virulence and environmental fitness determinants in pathogenic Acinetobacter species;
• Molecular mechanisms responsible for biofilm growth and environmental persistence of Acinetobacter;
• Management, therapeutics, and strategies for the prevention and control of infections caused by Acinetobacter;
• Innovative strategies to tackle the interplay between virulence and antimicrobial resistance of Acinetobacter.
Submission's of local surveillance studies of antimicrobial resistance in Acinetobacter baumannii is discouraged.
Keywords: Acinetobacter, antimicrobial resistance, genomic epidemiology, virulence, environmental fitness
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.