Research Topic

Innovative Technologies Addressing the Problem of Screw Loosening in Spinal Fusion Surgery

About this Research Topic

Although spinal fusion is a very common intervention and the technique has been refined in previous decades, insufficient screw hold and screw loosening still pose a relevant clinical problem with an incidence of about 10% in rigid fusion constructs. This rate is increased in motion-preserving instrumentations and in patients with low bone quality such as those with osteoporosis. In a recent study, the risk of screw loosening in vertebrae with low bone quality was found to be over 60%. Revision surgery is required in a significant part of these patients!

New technologies are required that directly address the high complication rate of screw loosening in spinal fusion surgery. Different approaches could be successful in achieving this aim:

- Computational analysis with the help of numerical models that allow patient-specific assessment of the screw-bone-interface to identify risk patients during preoperative planning.
- Novel screw trajectories such as individually optimized trajectories to improve screw-hold in the vertebral body.
- Innovative and novel implant designs that minimize the risk of loosening due to improved screw-hold.

The goal of this Research Topic is to stimulate leading research groups and to align global "research power“ to work towards answering the unsolved issue of screw loosening.

This Research Topic aims to attract Methods, Original Research, Brief Reports, and Review papers from worldwide specialists in spine biomechanics. It will offer a unique collection of knowledge and discussions for the improvement of current techniques or the development of preoperative planning approaches for addressing one of the major complications in spinal fusion surgery. Experimental studies that have been performed to improve the understanding of the failure behavior during screw loosening are also welcomed.


Keywords: Spinal Biomechanics, Screw Loosening, Spinal Fusion Surgery, Screw-Bone-Interface


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Although spinal fusion is a very common intervention and the technique has been refined in previous decades, insufficient screw hold and screw loosening still pose a relevant clinical problem with an incidence of about 10% in rigid fusion constructs. This rate is increased in motion-preserving instrumentations and in patients with low bone quality such as those with osteoporosis. In a recent study, the risk of screw loosening in vertebrae with low bone quality was found to be over 60%. Revision surgery is required in a significant part of these patients!

New technologies are required that directly address the high complication rate of screw loosening in spinal fusion surgery. Different approaches could be successful in achieving this aim:

- Computational analysis with the help of numerical models that allow patient-specific assessment of the screw-bone-interface to identify risk patients during preoperative planning.
- Novel screw trajectories such as individually optimized trajectories to improve screw-hold in the vertebral body.
- Innovative and novel implant designs that minimize the risk of loosening due to improved screw-hold.

The goal of this Research Topic is to stimulate leading research groups and to align global "research power“ to work towards answering the unsolved issue of screw loosening.

This Research Topic aims to attract Methods, Original Research, Brief Reports, and Review papers from worldwide specialists in spine biomechanics. It will offer a unique collection of knowledge and discussions for the improvement of current techniques or the development of preoperative planning approaches for addressing one of the major complications in spinal fusion surgery. Experimental studies that have been performed to improve the understanding of the failure behavior during screw loosening are also welcomed.


Keywords: Spinal Biomechanics, Screw Loosening, Spinal Fusion Surgery, Screw-Bone-Interface


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

20 February 2022 Abstract
20 April 2022 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

20 February 2022 Abstract
20 April 2022 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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