Skip to main content

About this Research Topic

Submission closed.

Given the success of Volume I of this Research Topic, and how rapid the subject area is evolving, we are pleased to announce the launch of Chronic Liver Disease: New Targets and New Mechanisms ...

Given the success of Volume I of this Research Topic, and how rapid the subject area is evolving, we are pleased to announce the launch of Chronic Liver Disease: New Targets and New Mechanisms - Volume II

The liver is mainly composed of hepatocytes, cholangiocytes, liver sinusoidal endothelial cells (LSECs), hepatic stellate cells (HSCs), and Kupffer cells. These cells cooperatively regulate hepatic function in numerous physiological processes, including glucose metabolism, lipid, cholesterol homeostasis, energy balance, blood volume regulation, immune responses. However, the liver is also vulnerable to multiple pathogenic factors, such as viral hepatitis, alcoholic liver disease (ALD), metabolic associated fatty liver disease (MAFLD), autoimmune liver disease, liver cirrhosis, and hepatocellular carcinoma (HCC), and their complications. Liver diseases affect millions of people worldwide and is a substantial health burden in many countries. Although significant advances have been made in preventing liver disease, the global morbidity and mortality rate of liver diseases remains high. It is urgent to find new molecular and cellular mechanisms underlying the development of chronic liver diseases and to support the devolvement of new therapeutic targets.

The present Research Topic aims to report the most recent molecular and cellular mechanisms of chronic liver diseases. The topic will be open to review and research articles that focus on, but not limited to, the following themes:

1. Novel mechanisms of chronic liver diseases, such as viral hepatitis, alcoholic liver disease, metabolic associated fatty liver disease (MALFD) & metabolic associated steatohepatitis (NASH), Liver fibrosis/cirrhosis, autoimmune liver disease, drug-induced liver injury (DILI), hepatocellular carcinoma, and cholangiocarcinoma, etc.

2. New technology and new tools in the study of chronic liver diseases

3. Novel therapeutic targets for chronic liver diseases

4. Epigenetics of chronic liver diseases

5. Inflammation regulation in chronic liver diseases

6. The role of liver cells in the development of chronic liver diseases

Keywords: #CollectionSeries, Chronic liver diseases, liver fibrosis, viral hepatitis, metabolic associated fatty liver disease, autoimmune liver disease, liver cirrhosis, hepatocellular carcinoma


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Topic Editors

Loading..

Topic Coordinators

Loading..

Recent Articles

Loading..

Articles

Sort by:

Loading..

Authors

Loading..

views

total views views downloads topic views

}
 
Top countries
Top referring sites
Loading..

Share on

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.