Research Topic

Genetics of Acquired Antimicrobial Resistance in Animal and Zoonotic Pathogens

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About this Research Topic

Development and spread of antimicrobial resistance is the result of an evolutionary process by which microorganisms adapt to antibiotics through several mechanisms including alteration of drug target by mutation and horizontal transfer of resistance genes. The concomitant occurrence of independent ...

Development and spread of antimicrobial resistance is the result of an evolutionary process by which microorganisms adapt to antibiotics through several mechanisms including alteration of drug target by mutation and horizontal transfer of resistance genes. The concomitant occurrence of independent antimicrobial resistance mechanisms is a serious threat to human health and has appeared in several emerging epidemic clones over the past decade in humans and also in animals. The increasing prevalence of antimicrobial drug resistance among animal and zoonotic foodborne pathogens is of particular concern for public health.

This Research Topic will focus on acquired antimicrobial resistance mechanisms in animal and zoonotic pathogens. All mechanisms will be considered such as target modification, protection of the target, efflux, decreased permeability, enzymatic inactivation. Emerging mobile elements harboring new resistance genes or resistance islands will be of particular interest for this topic.


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