Research Topic

Biology and evolution of reduced-genome microbes

  • Submission closed.

About this Research Topic

An interesting trend in cell interaction is the evolution of intracellular microorganisms, such as parasites and endosymbionts, which frequently present a reduced genome, usually accompanied by decreased metabolic and/or cellular capabilities. Such reduction is noticed in bacteria and in unicellular ...

An interesting trend in cell interaction is the evolution of intracellular microorganisms, such as parasites and endosymbionts, which frequently present a reduced genome, usually accompanied by decreased metabolic and/or cellular capabilities. Such reduction is noticed in bacteria and in unicellular eukaryotes, such as fungi and protozoa, when they are compared with their most closely related free-living relatives, and points towards significant aspects of genomic and cellular evolution. Living together brings about genome shortening, including genes for DNA repair and transcriptional regulation, loss of mobile elements, lowering of GC content, reduction or loss of codon-usage bias and diminution of intergenic region length that often leads to gene overlapping. Other interesting aspects of intracellular life are related to gene loss from the endosymbiont or parasite, or transfer of endosymbiont genes to the host nucleus. A diminished metabolic capability for the intracellular organism usually results in these instances, although biosynthetic pathways required by interaction with the host(s) are typically maintained. A notorious aspect of intracellular life is organelle origin, such as the mitochondrion and the chloroplast, originated from mutualistic relationships between prokaryotes and eukaryotes. Furthermore, symbiosis as a whole, which comprehends associations ranging from beneficial to harmful, has been investigated in environmental impact studies as well as in health programs to control several types of diseases.

The aim of this Research Topic is to highlight the latest research on all aspects of the biology, evolution, and biochemistry of host-parasite and host-endosymbiont interactions. Works on unicellular eukaryotes and/or bacterial lineages will be emphasized.


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Recent Articles

Loading..

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Topic Editors

Loading..

Submission Deadlines

Submission closed.

Participating Journals

Loading..

Topic Editors

Loading..

Submission Deadlines

Submission closed.

Participating Journals

Loading..
Loading..

total views article views article downloads topic views

}
 
Top countries
Top referring sites
Loading..

Comments

Loading..

Add a comment

Add comment
Back to top