Skip to main content

About this Research Topic

Submission closed.

Acinetobacter baumannii is a common pathogen and the emerged antibiotic resistance has been steadily spreading recently. Due to the rapid development of antibiotic resistance, infection with A. baumannii is difficult to treat, and it has been recognized as a global public health threat. ...

Acinetobacter baumannii is a common pathogen and the emerged antibiotic resistance has been steadily spreading recently. Due to the rapid development of antibiotic resistance, infection with A. baumannii is difficult to treat, and it has been recognized as a global public health threat. Effective treatments for A. baumannii infection are limited because the molecular epidemiology and antibiotic resistance mechanism are not well elucidated, leading to increased mortality rates and healthcare costs.
In recent years, there have been increasing reports of MDR and XDR A. baumannii infection worldwide. Several known pathogenic factors, including lipopolysaccharide, capsular polysaccharides, protein secretion systems, efflux pumps and biofilm formation, have been reported to be involved in antibiotic resistance, environmental persistence, host-pathogen interactions, and immune evasion. However, the specific mechanism remains unclear.
The exploration of the molecular epidemiology and antibiotic resistance mechanisms of A. baumannii is of great significance for the therapeutic development of A. baumannii infection.
This Research Topic focuses on the molecular epidemiology and antibiotic resistance mechanism of A. baumannii to novel antibacterial drugs, including but not limited to tigecycline, eravacycline, colistin, cefiderocol.
We welcome high-quality contributions, including Original Research and Review, addressing the following topics:
(1)Multicenter molecular epidemiology of A. baumannii to novel antibacterial drugs
(2)Antibiotic resistance mechanism of A. baumannii to novel antibacterial drugs
(3)In vivo evolution of A. baumannii under novel antimicrobial therapy
(4)Changes in host immune response during the treatment of A. baumannii with novel antibacterial drugs

Keywords: Acinetobacter, molecular epidemiology, antibiotic resistance mechanism, novel antibacterial drugs


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Topic Editors

Loading..

Topic Coordinators

Loading..

Recent Articles

Loading..

Articles

Sort by:

Loading..

Authors

Loading..

views

total views views downloads topic views

}
 
Top countries
Top referring sites
Loading..

Share on

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.