About this Research Topic
Moreover associated disorders like obesity, hypertension and entire spectrum of metabolic syndrome have been seen to be worsened during and after COVID. The mechanisms leading to a variable degree of metabolic derangements in different populations of COVID-19 patients needs to be studied in detail and suitable animal models or organ on chips can be designed to understand the same. The correlation of the persistence of insulin resistance with other comorbidities such as obesity, hypertension, atherosclerosis, and cardiovascular disorders also can be studied in retrospective as well as prospective cohort studies involving multiple centers across the globe. Studies also need to be conducted to highlight the inputs of individual immune responses in aggravating or mitigating the risk factors for a wide spectrum of metabolic derangements .Data showing the action or effects of drugs modulating insulin resistance in COVID-19 patients during and after recovery also needs to be analyzed for better management of patients.
Articles on (but not limited to) the following topics are welcome:
• Mechanisms of metabolic disorders in COVID-19
• Correlation of associated comorbidities with insulin resistance and COVID-19
• Experimental designs for understanding metabolic disorders in COVID-19
• Immune modulation and genetic regulation of metabolic disorders in an individual
• Patient data showing transient and long-standing hyperglycemia with measurements of HOMA-IR (Homeostatic Model Assessment for Insulin Resistance)
• Predicting an algorithm for the development of insulin resistance in an individual affected with SARs-CoV2.
• Effect of long standing COVID on alteration of signaling mechanisms leading to metabolic syndrome
• Experiments to study the link of long standing COVID with altered lipid metabolism, insulin resistance, obesity and adipocytokine signaling
• Role of drugs in modulating metabolic disorders during and after COVID 19
Type of articles: Review articles, Systematic Review and Meta-analysis, original research articles, Retrospective and Prospective Cohort studies, Experimental studies with or without clinical interventions
Keywords: Insulin Resistance, SARs-CoV2, Diabetes Mellitus, Hyperglycemia, Metabolic diseases
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.