About this Research Topic
Microfluidics has emerged as a promising technology, in which fluids are manipulated in microscale channels and chambers, allowing for fast and precise diagnosis of diseases in both humans and animals, as well as for food and environmental testing. They are highly sensitive and specific, allowing for the detection of even low concentrations of infectious agents, and are capable of providing rapid and accurate results. Additionally, these devices exhibit easy operation making them ideal for use in resource-limited and remote settings. A plethora of microfluidic innovations in recent years have now made multiplexed diagnostic devices for deployment at the point-of care medicine (POC). These devices have the capability to execute multiple tests in parallel, discerning diverse pathogens within a single sample. This characteristic is especially pivotal for zoonotic pathogen detection as they possess intricate transmission dynamics and frequently trigger coinfection in both animals and humans. Furthermore, the integration of microfluidic devices with various detection systems including optical, electrochemical, and mass spectrometry has enabled the development of sophisticated technologies that can significantly improve disease control and outbreak management in One Health. Consequently, the continued advancement of microfluidic technologies can pave the way for the implementation of innovative solutions for detecting and combating pathogens that threaten the health of humans, animals, and the environment.
We welcome the submission of Original Research, Review, Mini Review, and Perspective articles on themes including, but not limited to:
• Potential advancements in microfluidic technology for enhancing the sensitivity, specificity, and speed of pathogen detection.
• Development of multiplexed microfluidic devices for the simultaneous detection of multiple pathogens (for e.g., zoonotic, foodborne, and waterborne) in a single sample.
• Integration of microfluidic devices with artificial intelligence and machine learning algorithms for improved detection accuracy and real-time analysis of data.
• Utilization of microfluidics in point-of-care (POC) testing and remote monitoring for rapid response to pathogen outbreaks (In the context of One Health).
• Advancements in manufacturing and commercialization of microfluidic devices for wider accessibility and affordability.
• Exploration of new biomarkers and targets for one health pathogens detection using microfluidics.
• Collaborations between researchers in various disciplines to drive innovation and adoption of microfluidic technology for global health security.
• Home testing or self-testing kits, system integration and internet of things (IoT).
Topic Editor Dr. Yujing Song is co-employed by 454 Corporation. All other Topic Editors declare no competing interests with regards to the Research Topic subject.
Keywords: One Health, Microfluidics, Point-of-Care (POC), Affordable, DIY-based, Wearable, Smart-Phone
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