About this Research Topic
In this Research Topic, we provide an integrated description to unravel the intricate interplay between metabolic regulation and the immune response in HCC, along with their implications on therapeutic targeting and overcoming therapy resistance. We welcome submissions in the relevant fields, with a particular focus on, but not limited to:
1) Immune subtype of HCC
2) Novel roles of immunometabolism in HCC progression and drug resistance
3) Predictive or therapeutic targets of immunometabolism in HCC
4) Implications of cancer and immune cell metabolism on immunotherapy for HCC
5) Emerging approaches for testing and modeling tumor immunometabolism interactions
Please note: manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) are out of scope for this section and will not be accepted as part of this Research Topic.
Keywords: immunometabolism, tumor microenvironment, hepatocellular carcinoma
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.