Acinetobacter spp. is a genus of bacteria known for its remarkable adaptability and ability to thrive in diverse environments, commonly found in hospitals, especially in intensive care units. These gram-negative bacteria are characterized by their robustness and resistance to various antibiotics, posing a significant challenge in healthcare settings. Acinetobacter baumannii is the most frequently isolated pathogen of this species. The best-known mechanism of antibiotic resistance are beta-lactamases such as cephalosporinases and carbapenemases. A. baumanni, which is highly virulent, tends to display multiple resistance mechanisms, posing a serious risk to patients with weakened immune systems.
There are continuous and ongoing efforts to understand the structural features and mode of action of Acinetobacter spp., vital in driving scientific discovery towards prevention and treatment strategies against pneumonia, urinary tract infections, bloodstream infections, osteomyelitis, and wound infection etc. Through this research topic, we aim to explore the scientific gaps associated with our understanding of Acinetobacter spp. and its importance in designing better drugs, and treatment modalities and preventing/overcoming antibiotic resistance.
The current Research Topic aims to highlight the latest scientific findings on Acinetobacter spp. in the following areas:
- Pathogenesis and resistance mechanisms developed by the species.
- Host-pathogen interaction and immune evasion mechanisms.
- Prevention strategies to stem the infection.
- Novel treatment strategies against the infection.
Dr. Ramdin received financial support from Merck/MSD and Shionogi. All other Topic Editors declare no competing interests.
Acinetobacter spp. is a genus of bacteria known for its remarkable adaptability and ability to thrive in diverse environments, commonly found in hospitals, especially in intensive care units. These gram-negative bacteria are characterized by their robustness and resistance to various antibiotics, posing a significant challenge in healthcare settings. Acinetobacter baumannii is the most frequently isolated pathogen of this species. The best-known mechanism of antibiotic resistance are beta-lactamases such as cephalosporinases and carbapenemases. A. baumanni, which is highly virulent, tends to display multiple resistance mechanisms, posing a serious risk to patients with weakened immune systems.
There are continuous and ongoing efforts to understand the structural features and mode of action of Acinetobacter spp., vital in driving scientific discovery towards prevention and treatment strategies against pneumonia, urinary tract infections, bloodstream infections, osteomyelitis, and wound infection etc. Through this research topic, we aim to explore the scientific gaps associated with our understanding of Acinetobacter spp. and its importance in designing better drugs, and treatment modalities and preventing/overcoming antibiotic resistance.
The current Research Topic aims to highlight the latest scientific findings on Acinetobacter spp. in the following areas:
- Pathogenesis and resistance mechanisms developed by the species.
- Host-pathogen interaction and immune evasion mechanisms.
- Prevention strategies to stem the infection.
- Novel treatment strategies against the infection.
Dr. Ramdin received financial support from Merck/MSD and Shionogi. All other Topic Editors declare no competing interests.
