Research Topic

Systemic Lupus Erythematosus and Antiphospholipid Syndrome

About this Research Topic

Systemic Lupus Erythematosus (SLE) is the prototypical autoimmune disease, characterized by an extreme variety of anti-nuclear antibodies and by different clinical presentations. Antiphospholipid Syndrome (APS) is characterized by the presence of arterial or venous thrombosis and anti-phospholipid antibodies. SLE and APS frequently occur within the same patient. Both APS and SLE have unknown etiologies and their pathogenetic mechanism(s) remain poorly understood.

The aim of this Research Topic is to link bench to bed-side research on SLE and APS, to help us unravel the cellular and molecular basis of these diseases, with the ultimate goal of defining new diagnostic and therapeutic tools for SLE and APS. This Research Topic will cover novel findings and reviews that cover topics including, but not limited to:

1. SLE or APS and pregnancy;
2. SLE/APS-associated atherosclerosis and/or thrombosis;
3. Neuropsychiatric involvement in SLE and APS disease;
4. Lymphomas associated with SLE and APS;
5. Novel biomarkers for SLE and APS;
6. Identification of new immune modulators of SLE and APS;
7. The role of immune cells in SLE and APS;
8. The role of the microbiome in SLE and APS and
9. Nanomedicines for SLE and APS treatment.

We welcome the submission of the following article types to this Research Topic: Original Research, Review, Methods, Protocols, Technology Reports, Mini-Review and Clinical Trial.


Keywords: Systemic Lupus Erythematosus, Antiphospholipid Syndrome, Autoimmunity


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Systemic Lupus Erythematosus (SLE) is the prototypical autoimmune disease, characterized by an extreme variety of anti-nuclear antibodies and by different clinical presentations. Antiphospholipid Syndrome (APS) is characterized by the presence of arterial or venous thrombosis and anti-phospholipid antibodies. SLE and APS frequently occur within the same patient. Both APS and SLE have unknown etiologies and their pathogenetic mechanism(s) remain poorly understood.

The aim of this Research Topic is to link bench to bed-side research on SLE and APS, to help us unravel the cellular and molecular basis of these diseases, with the ultimate goal of defining new diagnostic and therapeutic tools for SLE and APS. This Research Topic will cover novel findings and reviews that cover topics including, but not limited to:

1. SLE or APS and pregnancy;
2. SLE/APS-associated atherosclerosis and/or thrombosis;
3. Neuropsychiatric involvement in SLE and APS disease;
4. Lymphomas associated with SLE and APS;
5. Novel biomarkers for SLE and APS;
6. Identification of new immune modulators of SLE and APS;
7. The role of immune cells in SLE and APS;
8. The role of the microbiome in SLE and APS and
9. Nanomedicines for SLE and APS treatment.

We welcome the submission of the following article types to this Research Topic: Original Research, Review, Methods, Protocols, Technology Reports, Mini-Review and Clinical Trial.


Keywords: Systemic Lupus Erythematosus, Antiphospholipid Syndrome, Autoimmunity


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

31 January 2018 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

31 January 2018 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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