About this Research Topic
Particularly, supplements such as omega-3, pre- probiotics, polyphenols and vitamins A and C share common properties such as normalization of the altered intestinal microbiota and up-regulation of Treg cell function. Moreover, another common pathology is represented by inflammatory bowel disease (IBD) characterized by changes of the microbiota profiles and an exaggerated Th17 cell function. Some of the above cited supplements are very effective in the adjuvant treatment of patients with IBD. Allergic reactions are very spread all over the world and evidence has been provided that polyphenols, as an example of immunonutrient, seem to be very effective in the treatment of these diseases either experimentally or in clinical settings. Finally, immunonutrient supplementation has been shown to be very efficacious in the treatment of immunosenescence and its complications.
In conclusion, this Research Topic will encompass the immunological properties of major nutrients such as omega-3, polyphenols, pre – probiotics, vitamins and oligoelements, on the one hand. On the other hand, clinical trials based on these supplements for the treatment of chronic inflammatory disease such as obesity, cardiovascular pathologies, IBD, autoimmune disease, contact dermatitis and neurodegenerative disease will represent the major topics related to this Research Topic.
Keywords: Omega-3, Prebiotics, Probiotics, Polyphenols, Vitamins
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