Cancer remains one of the leading causes of morbidity and mortality worldwide. This is in large part because it has proved to be a very heterogeneous disease, where intra- and interindividual differences in cancer phenotypes limit the efficacy of monotherapy. The limitation in the effectiveness of traditional approaches in treating cancer has been largely overcome thanks to the development of a wide variety of novel nanoplatforms, such as nanoparticles, liposomes, micelles, polymer-drug conjugates, and dendrimers. The most recent trend in their development is oriented to a multidisciplinary and collaborative approach, that involves contributions from material sciences, biology, immunology, medicine as well as diagnostic techniques. Nanotechnology platforms that can combine both therapy and diagnosis are especially interesting. This approach allows combining targeted therapy and monitoring of efficacy with minimal invasiveness and systemic toxicity. Multifunctional nanomedicines combining targeting, therapy, sensitivity, and early-stage detection are highly advantageous. This is a multi-disciplinary research topic, focusing on nanotechnology for the diagnosis and treatment of tumors.
This Research Topic aims at collecting recent advances in theranostic nanoplatforms, with a special emphasis on originally designed systems. Nanoplatforms combining drug delivery, targeting, and tumor monitoring approaches could be of particular interest when designed to address the challenge to specifically reach tumors in specific body districts, or treat tumors of different stages.
We welcome submissions for Original research, Review, Opinion, and Methods papers around the themes of Multifunctional nanoplatforms (nanoparticles, liposomes, etc), particularly combining therapy with targeting or monitoring of efficacy, including:
- Production of such nanoplatforms, including with upscaling or at GMP grade
- Regulatory issues
- Design and formulation
- In vivo application
Cancer remains one of the leading causes of morbidity and mortality worldwide. This is in large part because it has proved to be a very heterogeneous disease, where intra- and interindividual differences in cancer phenotypes limit the efficacy of monotherapy. The limitation in the effectiveness of traditional approaches in treating cancer has been largely overcome thanks to the development of a wide variety of novel nanoplatforms, such as nanoparticles, liposomes, micelles, polymer-drug conjugates, and dendrimers. The most recent trend in their development is oriented to a multidisciplinary and collaborative approach, that involves contributions from material sciences, biology, immunology, medicine as well as diagnostic techniques. Nanotechnology platforms that can combine both therapy and diagnosis are especially interesting. This approach allows combining targeted therapy and monitoring of efficacy with minimal invasiveness and systemic toxicity. Multifunctional nanomedicines combining targeting, therapy, sensitivity, and early-stage detection are highly advantageous. This is a multi-disciplinary research topic, focusing on nanotechnology for the diagnosis and treatment of tumors.
This Research Topic aims at collecting recent advances in theranostic nanoplatforms, with a special emphasis on originally designed systems. Nanoplatforms combining drug delivery, targeting, and tumor monitoring approaches could be of particular interest when designed to address the challenge to specifically reach tumors in specific body districts, or treat tumors of different stages.
We welcome submissions for Original research, Review, Opinion, and Methods papers around the themes of Multifunctional nanoplatforms (nanoparticles, liposomes, etc), particularly combining therapy with targeting or monitoring of efficacy, including:
- Production of such nanoplatforms, including with upscaling or at GMP grade
- Regulatory issues
- Design and formulation
- In vivo application
